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Mitoxantrone hydrochloride

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Name

Mitoxantrone hydrochloride

EINECS 274-619-1
CAS No. 70476-82-3 Density N/A
PSA 163.18000 LogP 2.39260
Solubility Soluble to 5 mM in water and to 75 mM in DMSO Melting Point 203-205 °C
Formula C22H28N4O6. 2HCl Boiling Point 805.7 °C at 760 mmHg
Molecular Weight 517.409 Flash Point 441.1 °C
Transport Information N/A Appearance N/A
Safety 53-36/37/39-45-22 Risk Codes 46-61-26/27/28
Molecular Structure Molecular Structure of 70476-82-3 (Mitoxantrone hydrochloride) Hazard Symbols ToxicT,VeryT+
Synonyms

9,10-Anthracenedione,1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, dihydrochloride(9CI);Bisantrone;CL 232315;DHAD;Immunex;Mitoxantrone dihydrochloride;NCI 301739;NSC 301739;Novantrone;Novatrone;Mitoxantrone HCL;

Article Data 5

Mitoxantrone hydrochloride Chemical Properties

Product Name: Mitoxantrone hydrochloride (CAS NO.70476-82-3)
IUPAC Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione dihydrochloride

Molecular formula: C22H30Cl2N4O6 
Formula weight: 517.4.
Melting point: 203-205 C.
Flash Point: 441.1 °C 
Enthalpy of Vaporization: 122.84 kJ/mol 
Boiling Point: 805.7 °C at 760 mmHg 
Vapour Pressure: 2.05E-27 mmHg at 25°C
Product Categories: API's

Mitoxantrone hydrochloride Uses

Used as antineoplastic agents.

Mitoxantrone hydrochloride Safety Profile

Hazard Codes : TToxic,T+Very
The Risk Statements information of  Mitoxantrone hydrochloride (CAS NO.70476-82-3):
46:  May cause heritable genetic damage  
61:  May cause harm to the unborn child 
26/27/28:  Very Toxic by inhalation, in contact with skin and if swallowed 
The Safety Statements information of  Mitoxantrone hydrochloride (CAS NO.70476-82-3):
22:  Do not breathe dust 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
53:  Avoid exposure - obtain special instruction before use 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection
RIDADR:  3249
WGK Germany : 3
RTECS : CB5748500
HazardClass : 6.1(b)
PackingGroup:  III

Mitoxantrone hydrochloride Specification

 Mitoxantrone hydrochloride , its CAS NO. is 70476-82-3, the synonyms are 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride ; Novantrone .

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