- N-Boc-N'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sufonyl)-L-arginine
- N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine
- N-Boc-N'-(2-chloro-Cbz)-L-ornithine
- N-Boc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
- N-Boc-N'-(9-xanthenyl)-L-glutamine
- N-Boc-N,N-bis(2-chloroethyl)amine
- N-Boc-N'-[(Allyloxy)carbonyl]-L-ornithine
- N-Boc-N'-acetyl-L-lysine
- N-Boc-N'-allyloxycarbonyl-D-lysine dicyclohexylamine salt
- N-Boc-N'-allyloxycarbonyl-L-2,4-diaminobutyric acid dicyclohexylamine salt
- 118754-53-3Benzene,2-bromo-1,3-dichloro-5-(trifluoromethyl)-
- 118757-11-25-Bromo-1-(phenylsulphonyl)-1H-indole
- 1187-58-2Propanamide, N-methyl-
- 1187582-53-1[(1-Methylpiperidin-4-yl)methyl]amine 2HCl
- 118758-48-8L-Proline, 3-phenyl-,(3R)-
- 1187-59-32-Propenamide,N-methyl-
- 1187732-72-41-(1-Ethyl-4-hydroxy-5-methyl-1H-pyrazol-3-yl)ethanone
- 1187-74-2Butanedioic acid,2-(2-oxopropyl)-, 1,4-diethyl ester
- 118777-77-8Aceticacid, 2-hydroxy-, compd. with N-[3-(dimethylamino)propyl]isooctadecanamide(1:1)
- 118779-53-6Acetamide,2-[(diphenylmethyl)sulfonyl]-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
N-Boc-N,N-bis(2-chloroethyl)amine |
EINECS | N/A |
| CAS No. | 118753-70-1 | Density | 1.149 g/cm3 |
| PSA | 29.54000 | LogP | 2.70110 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C9H17Cl2NO2 | Boiling Point | 290.662 °C at 760 mmHg |
| Molecular Weight | 242.145 | Flash Point | 129.588 °C |
| Transport Information | N/A | Appearance | White to off-white powder |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Carbamicacid, bis(2-chloroethyl)-, 1,1-dimethylethyl ester (9CI);Bis(2-chloroethyl)-N-(tert-butoxycarbonyl)amine;Bis(2-chloroethyl)-tert-butoxycarbonylamine;Bis(2-chloroethyl)carbamic acid1,1-dimethylethyl ester;Bis(2-chloroethyl)carbamic acid tert-butyl ester;Bis-(2-chloroethyl)carbamic acid tert-butyl ester;N,N-Bis(2-chloroethyl)carbamicacid tert-butyl ester;N-(tert-Butyloxycarbonyl)-N,N-bis(2-chloroethyl)amine;N-Boc-N,N-bis(2-chloroethyl)amine;N-Bocbis(2-chloroethyl)amine;N-tert-Butoxycarbonyl-N,N-bis(2-chloroethyl)amine;tert-ButylN,N-bis(2-chloroethyl)carbamate;tert-Butyl bis(2-chloroethyl)carbamate; |
Article Data | 58 |
N-Boc-N,N-bis(2-chloroethyl)amine Synthetic route
- 24424-99-5
di-tert-butyl dicarbonate
- 821-48-7
bis-(2-chloroethyl)amine hydrochloride
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
| Conditions | Yield |
|---|---|
| With triethylamine | 100% |
| In dichloromethane | 100% |
| With sodium hydroxide In dichloromethane at 20℃; for 18.5h; | 100% |
- 24424-99-5
di-tert-butyl dicarbonate
- 334-22-5
N,N-bis(chloro-2-ethyl)amine
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
| Conditions | Yield |
|---|---|
| With triethylamine In dichloromethane at 0 - 20℃; | 49% |
| With triethylamine In dichloromethane at 0 - 20℃; | 49% |
| With N-ethyl-N,N-diisopropylamine In dichloromethane |
- 24424-99-5
di-tert-butyl dicarbonate
- 821-48-7
bis-(2-chloroethyl)amine hydrochloride
A
- 473735-52-3
4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
B
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
| Conditions | Yield |
|---|---|
| With triethanolamine In dichloromethane | A 42% B n/a |
- 24424-99-5
di-tert-butyl dicarbonate
- 334-22-5
N,N-bis(chloro-2-ethyl)amine
B
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine In dichloromethane | |
| With N-ethyl-N,N-diisopropylamine In dichloromethane | |
| With N-ethyl-N,N-diisopropylamine In dichloromethane |
- 821-48-7
bis-(2-chloroethyl)amine hydrochloride
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 334-22-5
N,N-bis(chloro-2-ethyl)amine
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 75279-53-7
2-(4-chloro-2-fluoro-phenyl)acetonitrile
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 1093956-69-4
1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate
| Conditions | Yield |
|---|---|
| With sodium hydroxide; methyl tributylammonium chloride In water; toluene at 40℃; for 14h; Product distribution / selectivity; | 100% |
| Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 20℃; for 1h; Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 20℃; for 3h; | 38% |
| Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 23℃; for 0.166667h; Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 85℃; for 1.5h; | 38% |
| Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 23℃; for 0.166667h; Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 85℃; for 1.5h; | 38% |
| With sodium hydride In dimethyl sulfoxide |
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 57260-71-6
1-t-Butoxycarbonylpiperazine
| Conditions | Yield |
|---|---|
| With ammonium hydroxide at 60℃; for 5.5h; Time; | 94.3% |
- 123-30-8
4-amino-phenol
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 158985-25-2
tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate
| Conditions | Yield |
|---|---|
| With triethylamine In dichloromethane at 20℃; for 20h; | 93% |
- 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
- 10387-40-3
potassium thioacetate
- 321658-86-0
N-tert-butoxycarbonyl bis(2-thioacetoxyethyl)amine
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 20℃; for 48h; | 89.8% |
| In N,N-dimethyl-formamide at 20℃; for 72h; | 82% |
| In N,N-dimethyl-formamide at 20℃; for 48h; | 35% |
N-Boc-N,N-bis(2-chloroethyl)amine Specification
The N-Boc-N,N-bis(2-chloroethyl)amine, with CAS registry number of 118753-70-1, is also known as Carbamic acid, N,N-bis(2-chloroethyl)-, 1,1-dimethylethyl ester. It belongs to the product category of Pharmacetical. This chemical's molecular formula is C9H17Cl2NO2 and molecular weight is 242.1428. Its systematic name is tert-Butyl bis(2-chloroethyl)carbamate.
Physical properties about this chemical are: (1)ACD/LogP: 3.10; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.097; (4)ACD/LogD (pH 7.4): 3.097; (5)ACD/BCF (pH 5.5): 132.955; (6)ACD/BCF (pH 7.4): 132.955; (7)ACD/KOC (pH 5.5): 1152.806; (8)ACD/KOC (pH 7.4): 1152.806; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 29.54 Å2; (13)Index of Refraction: 1.471; (14)Molar Refractivity: 58.905 cm3; (15)Molar Volume: 210.649 cm3; (16)Surface Tension: 35.068 dyne/cm; (17)Enthalpy of Vaporization: 53.005 kJ/mol; (18)Vapour Pressure: 0.002 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES:CC(C)(C)OC(=O)N(CCCl)CCCl;
(2)InChI:InChI=1/C9H17Cl2NO2/c1-9(2,3)14-8(13)12(6-4-10)7-5-11/h4-7H2,1-3H3;
(3)InChIKey:FQZLNQAUUMSUHT-UHFFFAOYAR;
(4)Std. InChI:InChI=1S/C9H17Cl2NO2/c1-9(2,3)14-8(13)12(6-4-10)7-5-11/h4-7H2,1-3H3;
(5)Std. InChIKey:FQZLNQAUUMSUHT-UHFFFAOYSA-N.
What can I do for you?
Get Best Price
