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N-Ethylacetamide
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Name

N-Ethylacetamide

 EINECS 210-896-7
CAS No. 625-50-3 Density 0.866 g/cm3
PSA 29.10000 LogP 0.53330
Solubility Very soluble in water Melting Point -32ºC
Formula C4H9NO Boiling Point 205 ºC at 760 mmHg
Molecular Weight 87.1216 Flash Point 105.4 ºC
Transport Information N/A Appearance water white oily liquid.
Safety Moderately toxic by intraperitoneal route. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES. Risk Codes 23-24/25
Molecular Structure Molecular Structure of 625-50-3 (N-Ethylacetamide) Hazard Symbols Xn
Synonyms

Acetamidoethane;N-Acetylethylamine;N-Ethylacetamide;NSC 406307;

Article Data 84

N-Ethylacetamide Chemical Properties

Chemical Name: N-Ethylacetamide                  
IUPAC NAME: N-Ethylacetamide                                
CAS No.: 625-50-3
EINECS: 210-896-7
Molecular Formula: C4H9NO
Molecular Weight: 87.12 g/mol
Melting Point: -32°C
Polar Surface Area: 20.31 Å2
Index of Refraction: 1.397
Molar Refractivity: 24.2 cm3
Molar Volume: 100.4 cm3
Surface Tension: 24.8 dyne/cm 
Enthalpy of Vaporization: 44.12 kJ/mol 
Vapour Pressure: 0.256 mmHg at 25°C
Density: 0.866 g/cm3 
Flash Point: 105.4 °C
Boiling Point: 205 °C at 760 mmHg
Following is the structure:


Product Categories are Nitrogen Compounds ; Organic Building Blocks ; Protected Amines
The chemical synonymous of Ethylacetamide (CAS NO.625-50-3) are Acetic acid ethylamide ; N-Acetylethylamine ; N-Ethylacetamide ; Acetamidoethane ; Acetoethylamide ; Acetylethylamine ; Ethylacetamide ; N-Aethylacetamid 
Synonyms of: 4-04-00-00347 (Beilstein Handbook Reference) ; AI3-02181 ; Acetamidoethane ; Acetoethylamide ; BRN 0969292 ; EINECS 210-896-7 ; N-Aethylacetamid ; N-Aethylacetamid [German] ; N-Ethylacetamide ; NSC 406307 ; Acetamide, N-ethyl-                      

N-Ethylacetamide Uses

  Ethylacetamide (CAS NO.625-50-3) is used in organic synthesis, are also used as toughening agents, surfactants and solvents.

N-Ethylacetamide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LDLo intravenous 9600mg/kg (9600mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.
mouse LD50 intraperitoneal 3560mg/kg (3560mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.
rabbit LDLo intravenous 9410mg/kg (9410mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.
rat LD50 intraperitoneal 3130mg/kg (3130mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.
rat LD50 unreported 2500mg/kg (2500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 645, 1968.

N-Ethylacetamide Consensus Reports

Reported in EPA TSCA Inventory.

N-Ethylacetamide Safety Profile

Moderately toxic by intraperitoneal route. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.
Safety Statements about Ethylacetamide (CAS NO.625-50-3):
S23 Do not breathe vapour.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: AB8500000

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