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Cas Database |
| Name |
Nifurpipone |
EINECS | N/A |
| CAS No. | 24632-47-1 | Density | 1.41g/cm3 |
| PSA | 106.90000 | LogP | 0.67520 |
| Solubility | N/A | Melting Point |
167.5°C (rough estimate) |
| Formula | C12H17 N5 O4 | Boiling Point | °Cat760mmHg |
| Molecular Weight | 295.298 | Flash Point | °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
1-Piperazineaceticacid, 4-methyl-, (5-nitrofurfurylidene)hydrazide (8CI); 1-Piperazineaceticacid, 4-methyl-, [(5-nitro-2-furanyl)methylene]hydrazide (9CI);5-Nitro-2-furaldehyde 4-methylpiperazinoacethydrazone; 5-Nitro-2-furfuraldehydeN'-methyl-N-piperazinoacethydrazone; NP; NSC 276014; Nifurpipone; Rec 15-0122 |
Article Data | 3 |
Nifurpipone Chemical Properties
IUPAC Name: 2-(4-Methylpiperazin-1-yl)-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]acetamide
Synonyms of Nifurpipone (CAS NO.24632-47-1) : 1-Piperazineacetic acid, 4-methyl-, 2-[(1E)-(5-nitro-2-furanyl)methylene]hydrazide ; 2-(4-Methylpiperazin-1-yl)-N'-[(E)-(5-nitro-2-furyl)methylene]acetohydrazide ; 1-Piperazineacetic acid, 4-methyl-, ((5-nitro-2-furanyl)methylene)hydrazide (9CI) ; 2-Furaldehyde, 5-nitro-, (4-methylpiperazinylacetyl)hydrazone ; 4-Methyl-1-piperazineacetic acid (5-nitrofurfurylidene)hydrazide
InChI:InChI=1/C12H17N5O4/c1-15-4-6-16(7-5-15)9-11(18)14-13-8-10-2-3-12(21-10)17(19)20/h2-3,8H,4-7,9H2,1H3,(H,14,18)/b13-8+
CAS NO:24632-47-1
Molecular Formula:C12H17N5O4
Molecular Weight :295.2945
Molecular Structure :.png)
Index of Refraction: 1.634
Surface Tension: 59.7 dyne/cm
Density: 1.41 g/cm3
Nifurpipone Uses
Nifurpipone (CAS NO.24632-47-1) is synthetic antibacterial agents.
Nifurpipone Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 315mg/kg (315mg/kg) | Journal of Medicinal Chemistry. Vol. 14, Pg. 633, 1971. | |
| mouse | LD50 | intravenous | 295mg/kg (295mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 14(7), Pg. 1317, 1972. | |
| mouse | LD50 | oral | 880mg/kg (880mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975. |
| rabbit | LD50 | oral | 400mg/kg (400mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 14(7), Pg. 1317, 1972. | |
| rat | LD50 | intraperitoneal | 212mg/kg (212mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975. | |
| rat | LD50 | oral | 990mg/kg (990mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 73, 1975. |
Nifurpipone Consensus Reports
EPA Genetic Toxicology Program.
Nifurpipone Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. When Nifurpipone (CAS NO.24632-47-1) is heated to decomposition, it emits toxic fumes of NOx.
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