Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
Oleic acid diethanolamide |
EINECS | 202-281-7 |
CAS No. | 93-83-4 | Density | 0.96 g/cm3 |
PSA | 60.77000 | LogP | 4.83710 |
Solubility | N/A | Melting Point |
-18oC |
Formula | C22H43NO3 | Boiling Point | 525.6 °C at 760 mmHg |
Molecular Weight | 369.588 | Flash Point | 271.7 °C |
Transport Information | N/A | Appearance | clear liquid |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
9-Octadecenamide,N,N-bis(2-hydroxyethyl)-, (Z)-;Oleamide, N,N-bis(2-hydroxyethyl)-(6CI,7CI,8CI);Alkamide DO 280S;Alkamide DO-280;Alrosol O;Amisol ODE;Blaunon OL 05;Clindrol 200O;Clindrol 202O;Comperlan OD;Diethanolamine-oleicacid copolymer;Diethanololeamide;Emid 6545;Emulsifier WHC;Lauridit OD;Mackamide FTOA;Mackamide MO;Mackamide O;Marlamid D 1885;N,N-Bis(2-hydroxyethyl)oleamide;N,N-Diethanololeamide;Ninol 90201;NitreneNO;Oleamide DEA;Oleic diethanolamide;OleylamideDEA;Pamsurf;Romamid DT;Schercomid ODA;Stafoam DO;Stafoam DOS;Steinamid DO280SE;Varamide A 7;Vicamid 825;Witcamide 511C;Witcamide 511H; |
Article Data | 12 |
(Z)-9-octadecenoyl chloride
2,2'-iminobis[ethanol]
N,N-bis(2-hydroxyethyl)-oleamide
Conditions | Yield |
---|---|
In methanol; diethyl ether; water | 75% |
In dichloromethane at -40 - -10℃; Inert atmosphere; | 75.5% |
With dmap; triethylamine In dichloromethane at 0 - 20℃; |
Conditions | Yield |
---|---|
Stage #1: cis-Octadecenoic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h; Stage #2: 2,2'-iminobis[ethanol] In dichloromethane at 20℃; for 18h; | 58.2% |
With Candida antarctica lipase In acetonitrile at 60℃; for 24h; | 23% |
With Candida antarctica lipase In acetonitrile at 50℃; for 24h; Kinetics; | 12.1% |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 21 °C / Inert atmosphere 2: dichloromethane / -40 - -10 °C / Inert atmosphere View Scheme |
Conditions | Yield |
---|---|
With potassium hydroxide at 160℃; for 4h; Temperature; |
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 0 - 20℃; | 81% |
Conditions | Yield |
---|---|
Stage #1: 3,4,5-tribenzyloxybenzoic acid With dmap; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 0.5h; Stage #2: N,N-bis(2-hydroxyethyl)-oleamide In dichloromethane at 20℃; | 66% |
N,N-bis(2-hydroxyethyl)-oleamide
A
cis-Octadecenoic acid
B
2,2'-iminobis[ethanol]
Conditions | Yield |
---|---|
With Candida antarctica lipase In acetonitrile at 50℃; for 24h; Kinetics; |
N,N-bis(2-hydroxyethyl)-oleamide
pivaloyl chloride
N,n-bis(2-trimethylacetoxyethyl)oleamide
Conditions | Yield |
---|---|
With tetrabutyl-ammonium chloride; sodium hydroxide In water at 0 - 20℃; for 12.5h; |
Conditions | Yield |
---|---|
In water at 95℃; for 1h; Inert atmosphere; |
The Oleic acid diethanolamide, with the CAS registry number 93-83-4 and EINECS registry number 202-281-7, has the systematic name of (9Z)-N,N-bis(2-hydroxyethyl)octadec-9-enamide. It is a kind of yellow transparent viscous liquid, and the molecular formula of this chemical is C22H43NO3.
The physical properties of Oleic acid diethanolamide are as following: (1)ACD/LogP: 6.61; (2)# of Rule of 5 Violations: 1; (3)#H bond acceptors: 4; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 21; (6)Polar Surface Area: 38.77 Å2; (7)Index of Refraction: 1.488; (8)Molar Refractivity: 110.85 cm3; (9)Molar Volume: 384.6 cm3; (10)Polarizability: 43.94×10-24cm3; (11)Surface Tension: 38.5 dyne/cm; (12)Density: 0.96 g/cm3; (13)Flash Point: 271.7 °C; (14)Enthalpy of Vaporization: 92.02 kJ/mol; (15)Boiling Point: 525.6 °C at 760 mmHg; (16)Vapour Pressure: 3.04E-13 mmHg at 25°C.
Preparation and uses of Oleic acid diethanolamide: It can be prepared by the condensation reaction of coconut fatty acid with diethanolameine. As a nonionic surfactant, it is often used as thickening agent in shampoo and antistatic agent. What's more, it can improve the stability of foam, and increase the detergency of shampoo.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C(N(CCO)CCO)CCCCCCC\C=C/CCCCCCCC
(2)InChI: InChI=1/C22H43NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)23(18-20-24)19-21-25/h9-10,24-25H,2-8,11-21H2,1H3/b10-9-
(3)InChIKey: LPMBTLLQQJBUOO-KTKRTIGZBW
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Journal of the American College of Toxicology. Vol. 5(5), Pg. 415, 1986. | |
rat | LD50 | oral | 12400uL/kg (12.4mL/kg) | National Toxicology Program Technical Report Series. Vol. NTP-TR-481, Pg. 1999, |