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Name	PEMOLINE MAGNESIUM	EINECS	404-080-1
CAS No.	18968-99-5	Density	g/cm³
PSA	105.14000	LogP	0.38150
Solubility	N/A	Melting Point	>299.85°C
Formula	C₉H₁₀MgN₂O₄	Boiling Point	313.6 °C at 760 mmHg
Molecular Weight	234.52	Flash Point	143.4 °C
Transport Information	N/A	Appearance	N/A
Safety	Poison by ingestion. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x. See also MAGNESIUM COMPOUNDS and ORGANOMETALS.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	(2-imino-5-phenyl-4-oxazolidinonato(2-))diaquomagnesium;2-imino-5-phenyl-4(5h)-oxazolidinonmixt.withmagnesiumhydroxide;2-imino-5-phenyl-4-oxazolidinonemagnesiumchelate;2-imino-5-phenyl-4-oxazolidinonmixt.withmagnesiumhydroxide;abbott30400;bis(aquo)-n,n’-(2-imino-5-phenyl-4-oxazolidinone)magnesium(ii);magnesiumpemolate;pemolinandmagnesiumhydroxide

PEMOLINE MAGNESIUM Chemical Properties

MF: C₉H₁₀MgN₂O₄
MW: 234.49
Flash Point: 143.4 °C
Enthalpy of Vaporization: 55.46 kJ/mol
Boiling Point: 313.6 °C at 760 mmHg
Vapour Pressure of Pemoline magnesium (18968-99-5): 0.000493 mmHg at 25°C
IUPAC Name: magnesium 2-amino-5-phenyl-1,3-oxazol-4-one dihydroxide
Synonyms: (2-Imino-5-phenyl-4-oxazolidinonato(2-))diaquomagnesium ; 2-Imino-5-phenyl-4(5h)-oxazolidinonmixt.withmagnesiumhydroxide ; 2-imino-5-phenyl-4-oxazolidinonemagnesiumchelate ; 2-Imino-5-phenyl-4-oxazolidinonmixt.withmagnesiumhydroxide ; ABBOTT30400 ; Bis(aquo)-N,N’-(2-imino-5-phenyl-4-oxazolidinone)magnesium(II) ; Magnesiumpemolate ; Pemolinandmagnesiumhydroxide
Following is the molecular structure of Pemoline magnesium (18968-99-5):

PEMOLINE MAGNESIUM Uses

Pemoline magnesium (18968-99-5)can enhancement of Brain RNA Polymerases: The stimulation by magnesium pemoline of systems that synthesizebrain nucleic acid was studied in vivo and in vitro. There aredifferential effects between true RNA polymerase and pseudo-RNApolymerase. The selective stimulation of true RNA polymeraseby magnesium pemoline was not observed with stimulants of thecentral nervous system and psychotropic agents.

PEMOLINE MAGNESIUM Toxicity Data With Reference

The toxicity of Pemoline magnesium (18968-99-5):

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	149mg/kg (149mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) GASTROINTESTINAL: NAUSEA OR VOMITING	Clinical Pediatrics Vol. 18, Pg. 761, 1979.
monkey	LD50	oral	400mg/kg (400mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969.
mouse	LD50	intraperitoneal	487mg/kg (487mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969.
mouse	LD50	oral	500mg/kg (500mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: IRRITABILITY	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 181, Pg. 441, 1969.
rat	LD50	oral	485mg/kg (485mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 810, 1973.

PEMOLINE MAGNESIUM Safety Profile

Poison by ingestion. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.