Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Piperaquine Phosphate
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

Piperaquine Phosphate

 EINECS 202-303-5
CAS No. 4085-31-8 Density 1.292 g/cm3
PSA 38.74000 LogP 5.42990
Solubility N/A Melting Point 198-200 °C
Formula C29H32Cl2N6 Boiling Point 721.1 °C at 760 mmHg
Molecular Weight 535.519 Flash Point 389.9 °C
Transport Information N/A Appearance Almost wite powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 4085-31-8 (Piperaquine phosphate) Hazard Symbols N/A
Synonyms

Quinoline,4,4'-(trimethylenedi-4,1-piperazinediyl)bis[7-chloro- (7CI,8CI);Piperaquinoline;Piperaquine;

Article Data 5

Piperaquine Phosphate Synthetic route

109-64-8

1,3-dibromo-propane

837-52-5

7-chloro-4-piperazinylquinoline

4085-31-8

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane

Conditions
ConditionsYield
With sodium carbonate In water at 100℃; for 15h;
With triethylamine In methanol Product distribution / selectivity; Heating; Reflux;
86-98-6

4,7-dichloroquinoline

4085-31-8

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium iodide / isopropyl alcohol / 10 h / Reflux; Heating
2: triethylamine / methanol / Heating; Reflux
View Scheme
4085-31-8

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane

Piperaquine tetraphosphate

Conditions
ConditionsYield
With phosphoric acid; water In methanol; dichloromethane for 1 - 2h; Product distribution / selectivity;99.9%
4085-31-8

1,3-bis[1-(7-chloroquinolin-4-yl)piperazin-4-yl]propane

1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propanephosphate

Conditions
ConditionsYield
With phosphoric acid; water at 5 - 15℃; for 4 - 5h;
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 4085-31-8