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Prochlorperazine hydrogen maleate

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Name

Prochlorperazine hydrogen maleate

EINECS 201-511-3
CAS No. 84-02-6 Density N/A
PSA 184.22000 LogP 3.94460
Solubility Soluble to 25 mM in DMSO,Very slightly sol in water (<0.1% at 20°). Slightly sol in methanol, ethanol. Practically insol in ether Melting Point 228ºC
Formula C20H24ClN3S•2C4H4O4 Boiling Point 524.8 °C at 760 mmHg
Molecular Weight 606.096 Flash Point 271.2 °C
Transport Information N/A Appearance Off-White Powder
Safety 36 Risk Codes 20/21/22
Molecular Structure Molecular Structure of 84-02-6 (PROCHLORPERAZINE MALEATE) Hazard Symbols HarmfulXn
Synonyms

PROCHLORPERAZINE DIMALEATE;PROCHLORPERAZINE DIMALEATE SALT;PROCHLORPERAZINE MALEATE;2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine,dimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10h-phenothiazin(z)-2-but;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2);buccastem

 

Prochlorperazine hydrogen maleate Chemical Properties

IUPAC Name: (Z)-But-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
Synonyms: 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, (2Z)-2-butenedioate (1:2) ; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (2Z)-but-2-enedioate (1:2) ; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioate] ; Acide (2Z)-but-2-ènedioïque-2-chloro-10-[3-(4-méthylpipérazin-1-yl)propyl]-10H-phénothiazine (2:1)
Product Categories: Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Antagonists;Dopaminergics;Neurotransmitters
CAS NO: 84-02-6
Molecular Formula of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) : C28H32ClN3O8S
Molecular Weight of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) : 606.09
Molecular Structure of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) :
EINECS: 201-511-3
Flash Point: 271.2 °C
Enthalpy of Vaporization: 79.88 kJ/mol
Boiling Point: 524.8 °C at 760 mmHg
Vapour Pressure: 4.15E-11 mmHg at 25°C 
Appearance:Off-White Powder

Prochlorperazine hydrogen maleate Uses

 Prochlorperazine hydrogen maleate (CAS NO.84-02-6) has significant sedative effect, for acute and chronic mental illness, neurosis, and antiemetic.And can also be used for Meniere's syndrome.

Prochlorperazine hydrogen maleate Toxicity Data With Reference

1.    

orl-rat LD50:750 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 123 (1959),78.
2.    

scu-mus LD50:320 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,40.
3.    

ivn-mus LD50:142 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 123 (1959),78.

Prochlorperazine hydrogen maleate Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Cl, NOx, and SOx.

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