Phosphoramidous acid, dimethyl-, dimethyl ester

Base Information

• Chemical Name: Phosphoramidous acid, dimethyl-, dimethyl ester
• CAS No.: 20217-54-3
• Molecular Formula: C4H12NO2P
• Molecular Weight: 137.119
• DSSTox Substance ID: DTXSID10174064
• Nikkaji Number: J823.474D
• Wikidata: Q83044117
• Mol file: 20217-54-3.mol

Synonyms:Phosphoramidous acid, dimethyl-, dimethyl ester;20217-54-3;SCHEMBL17775451;DTXSID10174064

Chemical Property of Phosphoramidous acid, dimethyl-, dimethyl ester

Chemical Property:

• Vapor Pressure: 268mmHg at 25°C
• Boiling Point: 52.2°C at 760 mmHg
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 137.06056562
• Heavy Atom Count: 8
• Complexity: 56

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(OC)OC

Technology Process of Phosphoramidous acid, dimethyl-, dimethyl ester

There total 5 articles about Phosphoramidous acid, dimethyl-, dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + N,N-dimethylaminodichlorophosphane (683-85-2) → dimethoxy(dimethylamino)phosphine (20217-54-3)

Guidance literature:

With diethyl ether; triethylamine;

Reference yield:

methanol (67-56-1) + Hexamethylphosphorous triamide (1608-26-0) → dimethoxy(dimethylamino)phosphine (20217-54-3)

Guidance literature:

With N,N-dimethylammonium chloride; In benzene;

DOI:10.1021/jo00969a025

Reference yield:

methanol (67-56-1) + Hexamethylphosphorous triamide (1608-26-0) → phosphorous acid tetramethyldiamide methylester (17166-16-4) + dimethoxy(dimethylamino)phosphine (20217-54-3)

Guidance literature:

With dmap; 4-N,N-dimethylaminopyridine trifluoroacetate; In N,N-dimethyl-formamide; Product distribution;

DOI:10.1021/jo9823700

upstream raw materials:

methanol

N,N-dimethylaminodichlorophosphane

dimethyl amine

dimethyl chlorophosphite

Downstream raw materials:

N,N-dimethyl O,O-dimethyl phosphoramidothioate

2-dimethylamino-3,5-diisopropylidene-2,2-dimethoxy-2λ⁵-[1,4,2]dioxaphospholane

1,1-dicyanoethyl acetate

dimethyl phenylphosphonite

Refernces