2-(Aminooxy)ethanamine dihydrochloride

Base Information

• Chemical Name: 2-(Aminooxy)ethanamine dihydrochloride
• CAS No.: 37866-45-8
• Molecular Formula: C₂H₈N₂O*2ClH
• Molecular Weight: 149.02
• Hs Code.: 2922199090
• European Community (EC) Number: 412-310-7
• DSSTox Substance ID: DTXSID70559378
• Mol file: 37866-45-8.mol

Synonyms:2-(Aminooxy)ethanamine dihydrochloride;37866-45-8;O-(2-aminoethyl)hydroxylamine dihydrochloride;2-aminooxyethylamine dihydrochloride;2-(aminooxy)-1-ethanamine dihydrochloride;2-Aminoethoxyamine Dihydrochloride;2-(AMINOOXY)ETHYLAMINE 2HCL;2-(O-aminooxy)ethylamine dihydrochloride;O-(2-aminoethyl)hydroxylamine;dihydrochloride;2-(Aminooxy)-1-ethanamine DiHCl;C2H10Cl2N2O;Ethanamine, 2-(aminooxy)-, dihydrochloride;2-aminooxyethyl amine 2hcl;EC 412-310-7;SCHEMBL738325;H2NO(CH2)2NH2.2HCl;aminooxyethylamine dihydrochloride;DTXSID70559378;2-aminooxyethylaminedihydrochloride;2-aminoxyethylamine dihydrochloride;AMY10143;CS-M2746;2-(Aminooxy)ethanaminedihydrochloride;MFCD04117898;SC1781;2-(aminooxy)ethylamine.dihydrochloride;AKOS005070187;SB75662;3L-902;O-(2-aminoethyl)-hydroxylamine dihydrochloride;A873993;J-506200;2-(Aminooxy)ethan-1-amine--hydrogen chloride (1/2)

Chemical Property of 2-(Aminooxy)ethanamine dihydrochloride

Chemical Property:

• Vapor Pressure: 0.0115mmHg at 25°C
• Melting Point: 205-207°
• Boiling Point: 257.4 °C at 760 mmHg
• Flash Point: 109.5 °C
• PSA: 61.27000
• LogP: 1.84000
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 148.0170183
• Heavy Atom Count: 7
• Complexity: 17.1

Purity/Quality:

99.9% ^*data from raw suppliers

2-AminoethoxyamineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43-52/53
• Safety Statements: 24-37-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CON)N.Cl.Cl
• Uses: 2-AMinoethoxyaMine Dihydrochloride is used in the preparation of istaroxime analogs.

Technology Process of 2-(Aminooxy)ethanamine dihydrochloride

There total 5 articles about 2-(Aminooxy)ethanamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

→ 2-aminoethoxyamine dihydrochloride (37866-45-8,137270-05-4,157128-57-9)

Guidance literature:

Reference yield: 75.0%

C18H16N2O4 (1259519-97-5) → 2-aminoethoxyamine dihydrochloride (37866-45-8,137270-05-4,157128-57-9)

Guidance literature:

C₁₈H₁₆N₂O₄; With hydrazine; In ethanol;

With hydrogenchloride; In ethanol; water;

Reference yield: 74.0%

N-(2-aminoethoxy)benzamide (222960-38-5) → 2-aminoethoxyamine dihydrochloride (37866-45-8,137270-05-4,157128-57-9)

Guidance literature:

With hydrogenchloride; In water; for 4h; Concentration; Reflux;

upstream raw materials:

N-(2-aminoethoxy)benzamide

C₁₈H₁₆N₂O₄

Refernces

• 1、 -. "Novel synthesis method of Istaroxime". Paragraph 0131; 0132; 0133; 0134; 0135; 0136; 0137. . Retrieved 2016/10/10.
• 2、 -. "COMPOUNDS AND METHODS FOR TREATING NEOPLASIA". Page/Page column 98. . Retrieved 2011/04/18.