4,6-dichloro-2-fluoropyriMidine

Base Information

• Chemical Name: 4,6-dichloro-2-fluoropyriMidine
• CAS No.: 3824-45-1
• Molecular Formula: C4HCl2FN2
• Molecular Weight: 166.97
• Hs Code.: 2933599090
• Mol file: 3824-45-1.mol

Synonyms:2-fluoro-4,6-dichloropyrimidine;4,6-Dichlor-2-fluorpyrimidin;4,6-dichloro-2-fluoro-pyrimidine;2-Fluor-4.6-dichlorpyrimidin;

Chemical Property of 4,6-dichloro-2-fluoropyriMidine

Chemical Property:

• PSA: 25.78000
• LogP: 1.92250
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

4,6-Dichloro-2-fluoropyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-dichloro-2-fluoropyriMidine

There total 1 articles about 4,6-dichloro-2-fluoropyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

2,4,6-trichloropyrimidine (3764-01-0) → 2,4-dichloro-6-fluoropyrimidine (3833-57-6) + 2-fluoro-4,6-dichloropyrimidine (3824-45-1) + 2,4,6-trifluoropyrimidine (696-82-2)

Guidance literature:

With potassium fluoride; at 300 ℃; for 2h; Product distribution; C₄HCl₃N₂/KF = 4 x 10 E-2, other times, other temperatures, other molar ratios, other fluorinated products;

DOI:10.1016/S0022-1139(00)81784-4

upstream raw materials:

2,4,6-trichloropyrimidine

Refernces