o-Desmethyl metoclopramide

Base Information Edit

Chemical Name:o-Desmethyl metoclopramide
CAS No.:38339-95-6
Molecular Formula:C13H20ClN3O2
Molecular Weight:285.774
Hs Code.:
UNII:P5DX3Q3OG4
DSSTox Substance ID:DTXSID40191704
Nikkaji Number:J2.945.114A
Wikidata:Q27286217
ChEMBL ID:CHEMBL43695
Mol file:38339-95-6.mol

Synonyms:o-Desmethyl metoclopramide;38339-95-6;4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide;4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide;UNII-P5DX3Q3OG4;P5DX3Q3OG4;Metoclopramide specified impurity F [EP];CHEMBL43695;2-Hydroxy-4-amino-5-chloro-N,N-diethylaminoethylbenzamide;Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxy-;Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy-;4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide;Metoclopramide Imp. F (EP);Metoclopramide Hydrochloride Monohydrate Impurity F;Metoclopramide Impurity F;SCHEMBL8746079;DTXSID40191704;HPSMMIJTHMWCGC-UHFFFAOYSA-N;BDBM50023811;METOCLOPRAMIDE IMPURITY F [EP IMPURITY];A899648;EN300-19006996;Q27286217;4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-hydroxy-benzamide;N-[2-(Diethylamino)ethyl]-4-amino-5-chloro-2-hydroxybenzamide;4-amino-5- chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide;4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy benzamide;4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenz amide;Metoclopramide HCl Imp. F (EP): 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide

Suppliers and Price of o-Desmethyl metoclopramide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of o-Desmethyl metoclopramide Edit

Chemical Property:

Melting Point:134-136℃
Boiling Point:423.6±45.0 °C(Predicted)
PKA:7.83±0.48(Predicted)
PSA：82.08000
Density:1.230±0.06 g/cm3(Predicted)
LogP:2.85540
XLogP3:2.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:285.1244046
Heavy Atom Count:19
Complexity:287

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCNC(=O)C1=CC(=C(C=C1O)N)Cl

Technology Process of o-Desmethyl metoclopramide

There total 5 articles about o-Desmethyl metoclopramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%