Technology Process of 1-Cyclopentene-1-heptanoic acid,5-oxo-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester
There total 33 articles about 1-Cyclopentene-1-heptanoic acid,5-oxo-3-[(tetrahydro-2H-pyran-2-yl)oxy]-, Methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
for 4h;
Ambient temperature;
DOI:10.1139/v94-001
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 100 percent / N-bromosuccinimide, 2,2-azadiisobutyronitrile / CCl4 / 5 h / Heating
2: 62 percent / H2O / dioxane / 2.5 h / Heating
3: 72 percent / conc. HCl / 4 h / Ambient temperature
With
hydrogenchloride; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water;
In
1,4-dioxane; tetrachloromethane;
DOI:10.1139/v94-001
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 98 percent / imidazole / dimethylformamide / 0.17 h / 0 °C
2: 1.) Mg, 2.) cuprous iodide / 1.) tetrahydrofuran, reflux, 4.5 h, 2.) -10 deg C, 10 min
3: 87 percent / lithium tri-s-butylborohydride / tetrahydrofuran / 3 h / -78 °C
4: 79 percent / toluene-p-sulphonic acid / CH2Cl2 / 3 h / 0 °C
5: 97 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2.5 h / 0 °C
6: 100 percent / Jones reagent / acetone / 3.5 h / -20 °C
7: diethyl ether / 1 h
With
1H-imidazole; copper(l) iodide; jones reagent; tetrabutyl ammonium fluoride; L-Selectride; toluene-4-sulfonic acid; magnesium;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1039/P19810000599
