(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide

Base Information Edit

Chemical Name:(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide
CAS No.:402960-19-4
Molecular Formula:C9H18N2O2
Molecular Weight:186.254
Hs Code.:
Mol file:402960-19-4.mol

Synonyms:(3S)-3-Amino-N-cyclopropyl-2-hydroxy-hexanamide;Hexanamide, 3-amino-N-cyclopropyl-2-hydroxy-, (3S)-;(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide;HEXANAMIDE, 3-AMINO-N-CYCLOPROPYL-2-HYDROXY-,(3S)-;

Suppliers and Price of (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3S)-3-Amino-N-cyclopropyl-2-hydroxy-hexanamide
10mg
$ 165.00

Medical Isotopes, Inc.
(3S)-3-Amino-N-cyclopropyl-2-hydroxy-hexanamide
100 mg
$ 2200.00

Crysdot
(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide 95+%
1g
$ 518.00

Chemenu
(3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide 95%
1g
$ 489.00

American Custom Chemicals Corporation
(3S)-3-AMINO-N-CYCLOPROPYL-2-HYDROXYHEXANAMIDE 95.00%
5MG
$ 500.57

Total 44 raw suppliers

Chemical Property of (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide Edit

Chemical Property:

PSA：75.35000
Density:1.11
LogP:0.84450
Storage Temp.:2-8°C
Solubility.:Dimethyl Formamide, Dimethyl Sulfoxide, Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

(3S)-3-Amino-N-cyclopropyl-2-hydroxy-hexanamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Used in the preparation of tetrapeptide-based compounds useful in the inhibition of hepatitis C virus NS3·4A protease.

Technology Process of (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide

There total 13 articles about (3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 402959-34-6
(S)-3-(benzyloxycarbonyl)amino-2-hydroxyhexanoylcyclopropylamide

: 402960-19-4
3-(S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 18h;

Reference yield: 47.0%

: 1166397-39-2
N-cyclopropyl-3-amino-2-hydroxyhexanamide hydrochloride

: 402960-19-4
3-(S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide

Guidance literature:: N-cyclopropyl-3-amino-2-hydroxyhexanamide hydrochloride; With sodium hydroxide; In tert-butyl methyl ether; water; pH=9 - 10;

With Deoxycholic acid; In tetrahydrofuran; at 60 ℃; for 6h; Solvent; Temperature;

Reference yield:

: 6600-40-4,498-18-0
L-Norvaline

: 402960-19-4
3-(S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: hydrogenchloride / 6 h / Reflux; Inert atmosphere

2.1: potassium carbonate / water; tetrahydrofuran / 4 h / 20 °C

2.2: 2 h / 10 - 25 °C

3.1: N-ethyl-N,N-diisopropylamine; sulfur trioxide pyridine complex / toluene; dimethyl sulfoxide / 1 h / 0 °C / Inert atmosphere

3.2: 1 h / 0 °C

4.1: water; sodium dithionite / methanol / 0 °C / Cooling

4.2: 2 h / 25 °C

5.1: hydrogenchloride; water / 3 h / Reflux

5.2: Reflux

5.3: 3 h / 10 - 20 °C

6.1: methanol / 48 h / 70 °C

7.1: 5%-palladium/activated carbon; hydrogen / methanol / 48 h

With hydrogenchloride; sodium dithionite; 5%-palladium/activated carbon; water; hydrogen; sulfur trioxide pyridine complex; potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; water; dimethyl sulfoxide; toluene;