1,2-Cyclopentanediol

Base Information

• Chemical Name: 1,2-Cyclopentanediol
• CAS No.: 4065-92-3
• Molecular Formula: C5H10O2
• Molecular Weight: 102.133
• Hs Code.: 2906199090
• DSSTox Substance ID: DTXSID00275933
• Nikkaji Number: J80.740K
• Mol file: 4065-92-3.mol

Synonyms:1,2-Cyclopentanediol;4065-92-3;Cyclopentane-1,2-diol;MFCD00797992;1,2-Cyclopentanediol #;1,2-Cyclopentanediol, trans-;MFCD00082582;v1,2-Cyclopentanediol;SCHEMBL62738;1,2-Cyclopentanediol, cis-;cis-1,2-Dihydroxycyclopentane;DTXSID00275933;EINECS 225-757-6;NSC 15389;AKOS009157037;SB74656;SB84073;SB84237;AS-31921;BP-21495;SY007557;SY028304;AI3-26281;CS-0451973;FT-0623879;FT-0690230;FT-0695374;FT-0696714;FT-0734024;FT-0772459;EN300-75738;A873257;Z600452564

Chemical Property of 1,2-Cyclopentanediol

Chemical Property:

• PSA: 40.46000
• LogP: -0.10790
• Storage Temp.: 2-8°C
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 55.1

Purity/Quality:

98%min ^*data from raw suppliers

1,2-Cyclopentanediol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C(C1)O)O

Technology Process of 1,2-Cyclopentanediol

There total 24 articles about 1,2-Cyclopentanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclopentene (142-29-0) → cyclopentane-1,2-diol (4065-92-3,86703-52-8)

Guidance literature:

With N-methyl-2-indolinone; polysulfone microencapsulated OsO₄; In water; acetone; acetonitrile; at 20 ℃; for 0.333333h;

DOI:10.1016/j.tetlet.2006.05.138

Reference yield: 97.0%

Cyclopentene oxide (285-67-6) → cyclopentane-1,2-diol (4065-92-3,86703-52-8)

Guidance literature:

With N-methylpyrrolidine-2-one hydrotribromide; water; at 20 ℃; for 1.5h; regioselective reaction; Neat (no solvent);

DOI:10.1080/00397911.2010.493259

Reference yield: 94.7%

Cyclopentene oxide (285-67-6) → cyclopentane-1,2-diol (4065-92-3,86703-52-8) + Glutaraldehyde (111-30-8,29257-65-6,79215-57-9)

Guidance literature:

With dihydrogen peroxide; In water; at 34.84 ℃; for 1h; Concentration;

DOI:10.1039/c2ra22194b

upstream raw materials:

1,2-dibromo-cyclopentane

Cyclopentene oxide

acetic acid

cyclopentene

Downstream raw materials:

1,2-bis-phenylcarbamoyloxy-cyclopentane

Cyclopentene oxide

1,5-pentanedioic acid

Cyclopentane

Refernces

• 1、 Cousin, Tony,Chatel, Gregory,Andrioletti, Bruno,Draye, Micheline. "Oxidative cleavage of cycloalkenes using hydrogen peroxide and a tungsten-based catalyst: Towards a complete mechanistic investigation". . p. 235 - 242. Retrieved 2021/01/11.
• 2、 Liang, Xiaohang,Liu, Dan,Luo, Yibin,Peng, Xinxin,Shu, Xingtian,Xia, Changjiu. "Understanding the mechanism of N coordination on framework Ti of Ti-BEA zeolite and its promoting effect on alkene epoxidation reaction". . . Retrieved 2021/07/31.