4-(Chlorocarbonyl)phenyl sulfone

Base Information

• Chemical Name: 4-(Chlorocarbonyl)phenyl sulfone
• CAS No.: 4462-61-7
• Molecular Formula: C14H8Cl2O4S
• Molecular Weight: 343.187
• Hs Code.: 2916399090
• Mol file: 4462-61-7.mol

Synonyms:4.4'-Sulfonyl-dibenzoesaeure-dichlorid;4,4'-Sulfonyl-di-benzoylchlorid;4,4'-sulfonyl-di-benzoyl chloride;Benzoyl chloride,4,4'-sulfonylbis;

Chemical Property of 4-(Chlorocarbonyl)phenyl sulfone

Chemical Property:

• PSA: 76.66000
• LogP: 4.35820

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(Chlorocarbonyl)phenyl sulfone

There total 5 articles about 4-(Chlorocarbonyl)phenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

bis(4-carboxyphenyl)sulfone (2449-35-6) → 4,4′-sulfonyldibenzoyldichloride (4462-61-7)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 24h; Reflux;

DOI:10.1002/pola.24172

Reference yield:

4,4'-dicarbomethoxydiphenyl sulfone (3965-53-5) → 4,4′-sulfonyldibenzoyldichloride (4462-61-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol / Reflux

2: thionyl chloride; N,N-dimethyl-formamide / 24 h / Reflux

With thionyl chloride; N,N-dimethyl-formamide; potassium hydroxide; In ethanol;

DOI:10.1002/pola.24172

Reference yield:

→ 4,4′-sulfonyldibenzoyldichloride (4462-61-7)

Guidance literature:

With thionyl chloride;

upstream raw materials:

bis(4-carboxyphenyl)sulfone

4-(4-Chlorocarbonyl-benzenesulfonyl)-benzoic acid

4,4'-dicarbomethoxydiphenyl sulfone

Downstream raw materials:

N,N'-[4,4'-sulfonylbis(benzoyl)]-bis{4,4'-(p-fluorobenzyl)-1,2-dihydroisoquinaldonitrile}

p-{1-[4-(p-fluorobenzyl)isoquinolyl]carbonyl}diphenyl sulfone

dapsone

bis(p-anisyl)sulfone

Refernces

• 1、 Gibson, Harry W.,Brumfield, Kimberly K.,Grisle, Roger A.,Hermann, Christine K. F.. "Synthesis of heterocyclic monomers via Reissert chemistry". experimental part. p. 3856 - 3867. Retrieved 2011/11/13.