Technology Process of Benzoic acid, 4-nitro-2-(phenylamino)-
There total 7 articles about Benzoic acid, 4-nitro-2-(phenylamino)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanol; lithium hydroxide;
In
tetrahydrofuran; water;
Reflux;
DOI:10.1124/mol.113.087502
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / 20 - 130 °C
2: methanol; lithium hydroxide / water; tetrahydrofuran / Reflux
With
methanol; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; lithium hydroxide;
In
tetrahydrofuran; water;
1: |Buchwald-Hartwig Coupling;
DOI:10.1124/mol.113.087502
- Guidance literature:
-
Multi-step reaction with 3 steps
1: chloride derivative / 0 °C / Reflux
2: tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate / 20 - 130 °C
3: methanol; lithium hydroxide / water; tetrahydrofuran / Reflux
With
methanol; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; lithium hydroxide;
In
tetrahydrofuran; water;
2: |Buchwald-Hartwig Coupling;
DOI:10.1124/mol.113.087502