4-NITROPHENYL METHACRYLATE

Base Information

• Chemical Name: 4-NITROPHENYL METHACRYLATE
• CAS No.: 16522-41-1
• Molecular Formula: C10H9 N O4
• Molecular Weight: 207.186
• Mol file: 16522-41-1.mol

Synonyms:Methacrylicacid, p-nitrophenyl ester (6CI,8CI); 4-Nitrophenyl methacrylate; NSC 301496;p-Nitrophenyl methacrylate

Chemical Property of 4-NITROPHENYL METHACRYLATE

Chemical Property:

• Vapor Pressure: 6.15E-05mmHg at 25°C
• Melting Point: 93-94 °C
• Boiling Point: 345.4°Cat760mmHg
• Flash Point: 162.3°C
• PSA: 72.12000
• Density: 1.241g/cm³
• LogP: 2.59950

Purity/Quality:

99% ^*data from raw suppliers

4-NITROPHENYL METHACRYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITROPHENYL METHACRYLATE

There total 5 articles about 4-NITROPHENYL METHACRYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Methacryloyl chloride (920-46-7,26937-45-1) → 4-nitrophenyl methacrylate (16522-41-1)

Guidance literature:

With triethylamine; In chloroform; butanone; for 2h;

Reference yield: 58.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 1,2-propanediene (463-49-0) + carbon monoxide (201230-82-2) → 4-nitrophenyl methacrylate (16522-41-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 100 ℃; for 16h;

DOI:10.1016/S0040-4020(98)00115-X

Reference yield: 55.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) → 4-nitrophenyl methacrylate (16522-41-1)

Guidance literature:

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In dichloromethane; at 20 - 25 ℃; for 1h;

DOI:10.1016/j.tet.2020.131758

upstream raw materials:

4-nitro-phenol

Methacryloyl chloride

1,2-propanediene

carbon monoxide

Downstream raw materials:

S-p-nitrophenyl 2-methylpropanethioate

S-phenyl 2-methylpropenethioate

Refernces

• 1、 Li, Fang,Zhu, Yingchun,You, Bo,Zhao, Donghui,Ruan, Qichao,Zeng, Yi,Ding, Chuanxian. "Smart hydrogels co-switched by hydrogen bonds and π-π stacking for continuously regulated controlledrelease system". . p. 669 - 676. Retrieved 2010.
• 2、 -. "PH-responsive nano-drug delivery system and preparation method thereof". Paragraph 0062; 0065; 0066. . Retrieved 2020/12/10.