Ammonium methanesulfonate

Base Information

• Chemical Name: Ammonium methanesulfonate
• CAS No.: 22515-76-0
• Molecular Formula: CH4 O3 S . H3 N
• Molecular Weight: 113.137
• Hs Code.: 2923900090
• European Community (EC) Number: 621-178-1
• UNII: QJ4NW2YFV6
• DSSTox Substance ID: DTXSID10884893
• Mol file: 22515-76-0.mol

Synonyms:Ammonium methanesulfonate;22515-76-0;Ammonium methane sulfonate;azanium;methanesulfonate;ammoniummethanesulfonate;Methanesulfonic acid, ammonium salt;Methanesulfonic acid, ammonium salt (1:1);NSC-166292;SCHEMBL242728;DTXSID10884893;QHYIGPGWXQQZSA-UHFFFAOYSA-N;AKOS024429139

Chemical Property of Ammonium methanesulfonate

Chemical Property:

• Vapor Pressure: 0.000218mmHg at 25°C
• Melting Point: 198-201 °C (decomp)
• Boiling Point: 303.2°C at 760 mmHg
• Flash Point: 137.2°C
• PSA: 65.99000
• LogP: 0.90870
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 113.01466426
• Heavy Atom Count: 6
• Complexity: 79.2

Purity/Quality:

99%, ^*data from raw suppliers

Methanesulfonic acid, Ammonium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CS(=O)(=O)[O-].[NH4+]
• Uses: Methanesulfonic Acid, Ammonium Salt can be used to prepare an anti-cancer drug.

Technology Process of Ammonium methanesulfonate

There total 2 articles about Ammonium methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

methyl fluorosulfonate (558-25-8) → trimethylsilyl fluoride (420-56-4) + Hexamethyldisiloxane (107-46-0) + Ammonium methanesulfonate (22515-76-0) + hydrazinium mesylate (76391-43-0)

Guidance literature:

With O-Trimethylsilylhydroxylamine;

Reference yield:

ethyl valerimidate METHANESULFONIC acid salt (745814-07-7) + 1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine (134603-82-0) → 2-(1-TRITYL-1H-TETRAZOL-5-YL)-4'-(1''-ETHOXYPENTANAMINYL)BIPHENYL (745814-08-8) + Ammonium methanesulfonate (22515-76-0)

Guidance literature:

In toluene; at 20 ℃; for 12h;

Reference yield:

Ammonium methanesulfonate (22515-76-0) + 1-butyl-3-methylimidazolium chloride (79917-90-1) → 1-n-butyl-3-methylimidazolium methanesulfonate (342789-81-5)

Guidance literature:

1-butyl-3-methylimidazolium chloride; With potassium hydroxide; In tetrahydrofuran; Sonication;

Ammonium methanesulfonate; In water; at 20 ℃;

DOI:10.1016/j.tetlet.2009.05.015

upstream raw materials:

methyl fluorosulfonate

ethyl valerimidate METHANESULFONIC acid salt

1-(2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methanamine

Downstream raw materials:

1-n-butyl-3-methylimidazolium methanesulfonate

Refernces

• 1、 Brink, Klaus,Bliefert, Claus. "Mesylhydroxylamines, III. The Reaction of Methane Sulfonyl Fluoride and Hydroxyamine". . p. 1059 - 1062. Retrieved 2007/10/02.