Tricyclo[4.3.1.13,8]undecan-3-amine

Base Information

• Chemical Name: Tricyclo[4.3.1.13,8]undecan-3-amine
• CAS No.: 3048-63-3
• Molecular Formula: C₁₁H₁₉N
• Molecular Weight: 165.279
• Hs Code.: 2921300090
• Mol file: 3048-63-3.mol

Synonyms:3-Aminohomoadamantane;3-Homoadamantylamine; Homoadamantan-3-amine; JP 20

Chemical Property of Tricyclo[4.3.1.13,8]undecan-3-amine

Chemical Property:

• PSA: 26.02000
• LogP: 3.00430

Purity/Quality:

98%min ^*data from raw suppliers

Tricyclo[4.3.1.1~3,8~]undec-3-ylaminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Tricyclo[4.3.1.13,8]undecan-3-amine

There total 9 articles about Tricyclo[4.3.1.13,8]undecan-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H19N*HNO3 → 3-Aminohomoadamantan (3048-63-3)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1134/S1070428015120064

Reference yield:

Tricyclo<4.3.1.13.8>undecan-3-carbamidsaeure-methylester (4546-46-7) → 3-Aminohomoadamantan (3048-63-3)

Guidance literature:

With sodium hydroxide; In diethylene glycol; Heating;

DOI:10.1021/jm00288a019

Reference yield:

Homoadamantane-3-carboxylic acid (21898-91-9) → 3-Aminohomoadamantan (3048-63-3)

Guidance literature:

Multi-step reaction with 2 steps

2: NaOH / bis-(2-hydroxy-ethyl) ether / Heating

With sodium hydroxide; In diethylene glycol;

DOI:10.1021/jm00288a019

upstream raw materials:

Tricyclo<4.3.1.1^3.8>undecan-3-carbamidsaeure-methylester

3-bromohomoadamantane

acetonitrile

Homoadamantane-3-carboxylic acid

Downstream raw materials:

3-Hydroxyhomoadamantan

Refernces

• 1、 Aldrich,Hermann,Meier,Paulshock,Prichard,Snyder,Watts. "Antiviral agents. 2. Structure-activity relationships of compounds related to 1-adamantanamine.". . p. 535 - 543. Retrieved 2007/10/05.