2-Cyclohexen-1-ol, 4,4-dimethyl-

Base Information

• Chemical Name: 2-Cyclohexen-1-ol, 4,4-dimethyl-
• CAS No.: 5020-09-7
• Molecular Formula: C8H14O
• Molecular Weight: 126.199
• Hs Code.: 2906199090
• Mol file: 5020-09-7.mol

Synonyms:4,4-dimethyl-cyclohex-2-enol;4,4-dimethyl-2-cyclohexenol;4,4-dimethyl-2-cyclohexen-1-ol;2-Cyclohexen-1-ol,4,4-dimethyl;

Chemical Property of 2-Cyclohexen-1-ol, 4,4-dimethyl-

Chemical Property:

• PSA: 20.23000
• LogP: 1.72350

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Cyclohexen-1-ol, 4,4-dimethyl-

There total 6 articles about 2-Cyclohexen-1-ol, 4,4-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,4-dimethylcyclohexenone (1073-13-8) → 4,4-dimethyl-2-cyclohexen-1-ol (5020-09-7)

Guidance literature:

With potassium hydroxide; hydrogen; RuCl2<(S)-binap>(dmf)n*(R,R)-1,2-diphenylethylenediamine; In isopropyl alcohol; at 28 ℃; for 2h; under 3040 Torr;

DOI:10.1055/s-1997-6141

Reference yield: 98.0%

4,4-dimethylcyclohexenone (1073-13-8) → 4,4-dimethyl-cyclohexanol (932-01-4) + 4,4-dimethyl-2-cyclohexen-1-ol (5020-09-7)

Guidance literature:

With sodium tetrahydroborate; Nd(EBAB)Cl₃; In methanol; for 1h; Product distribution; Ambient temperature; other reagents: Ce(EBAB)Cl₃, Pr(EBAB)Cl₃, Yb(PBAB)Cl₃,;

Reference yield: 87.0%

6-benzyloxy-3,3-dimethylcyclohexene → 4,4-dimethyl-2-cyclohexen-1-ol (5020-09-7)

Guidance literature:

With naphthalen-1-yl-lithium; In tetrahydrofuran; at -25 ℃; for 1.16667h;

DOI:10.1016/S0040-4039(97)00345-6

upstream raw materials:

4,4-dimethylcyclohexenone

Downstream raw materials:

5,5-dimethyl-1,3-cyclohexadiene

6-chloro-3,3-dimethylcyclohex-1-ene

4,4-Dimethyl-2-cyclohexenylphenylsulfid

2-(4,4-dimethylcyclohex-2-enyl)isoindoline-1,3-dione

Refernces

• 1、 Hirano, Koji,Miura, Masahiro,Xu, Shibo. "Pd-catalyzed regioselective C?H alkenylation and alkynylation of allylic alcohols with the assistance of a bidentate phenanthroline auxiliary". supporting information. p. 9059 - 9064. Retrieved 2020/12/02.
• 2、 Rideau, Emeline,You, Hengzhi,Sidera, Mireia,Claridge, Timothy D. W.,Fletcher, Stephen P.. "Mechanistic Studies on a Cu-Catalyzed Asymmetric Allylic Alkylation with Cyclic Racemic Starting Materials". supporting information. p. 5614 - 5624. Retrieved 2017/04/27.