12,15-Octadecadienoic acid, 9-hydroxy-10-oxo-, (12Z,15Z)-

Base Information

• Chemical Name: 12,15-Octadecadienoic acid, 9-hydroxy-10-oxo-, (12Z,15Z)-
• CAS No.: 51146-89-5
• Molecular Formula: C18H30O4
• Molecular Weight: 310.42800
• Mol file: 51146-89-5.mol

Synonyms:9-Hydroxy-10-oxo,cis-12,cis-15-octadecadiensaeure;

Chemical Property of 12,15-Octadecadienoic acid, 9-hydroxy-10-oxo-, (12Z,15Z)-

Chemical Property:

• PSA: 74.60000
• LogP: 4.03430

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12,15-Octadecadienoic acid, 9-hydroxy-10-oxo-, (12Z,15Z)-

There total 13 articles about 12,15-Octadecadienoic acid, 9-hydroxy-10-oxo-, (12Z,15Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.8%

(12Z,15Z)-methyl 9-hydroxy-10-oxooctadeca-12,15-dienoate (359643-47-3) → (+/-)-9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid (51146-89-5)

Guidance literature:

With Lipase PS; In phosphate buffer; acetone; pH=7.0;

DOI:10.1246/cl.2003.844

Reference yield: 60.4%

9-[(tert-butyldimethylsilyl)oxy]-10-oxo-12(Z),15(Z)-octadecadienic acid (359643-49-5) + acetonitrile (75-05-8,26809-02-9) → (+/-)-9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid (51146-89-5)

Guidance literature:

With hydrogen fluoride; In water;

Reference yield:

(9Z,12Z,15Z)-octadeca-9-12,15-trienoic acid (463-40-1,1955-33-5,21661-10-9,21661-09-6,21661-13-2,21661-11-0) → (12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoic acid (955974-89-7) + 12-Hydroxy-octadecadien-(cis-9,cis-15)-saeure, Densipolsaeure (301664-23-3,7121-47-3) + (+/-)-9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid (51146-89-5) + C18H30O4 + 13-hydroxy-9Z,15Z-octadecadienoic acid + (9Z,12Z)-15-hydroxyoctadeca-9,12-dienoic acid (177931-23-6) + C18H32O3 + C18H30O4 + C18H30O4 + C18H30O4 + 12,13-DiHODE (85416-59-7) + (12Z,15Z)-9-Hydroxy-octadeca-12,15-dienoic acid + 15,16-DiHODE (140129-22-2) + (12Z,15Z)-10-hydroxy-12,15-octadecadienoic acid + (9Z,15Z)-13-hydroxy-12-oxo-9,15-octadecadienoic acid

Guidance literature:

With dihydrogen peroxide; oxygen; at 112 ℃; Mechanism; Flow reactor; Photolysis;

DOI:10.1021/jp508378z

upstream raw materials:

(12Z,15Z)-methyl 9-hydroxy-10-oxooctadeca-12,15-dienoate

Methyl oleate

methyl ester of azelaic acid aldehyde

9-hydroxyundec-10-enoic acid methyl ester

Refernces

• 1、 Nah, Theodora,Zhang, Haofei,Worton, David R.,Ruehl, Christopher R.,Kirk, Benjamin B.,Goldstein, Allen H.,Leone, Stephen R.,Wilson, Kevin R.. "Isomeric product detection in the heterogeneous reaction of hydroxyl radicals with aerosol composed of branched and linear unsaturated organic molecules". . p. 11555 - 11571. Retrieved 2015/02/19.
• 2、 -. "α-KETOL UNSATURATED FATTY ACID DERIVATIVES AND PLANT GROWTH REGULATORS CONTAINING THE SAME". Page/Page column 17-18. . Retrieved 2008/06/13.