Phenanthro[4,3-b]thiophene

Base Information

• Chemical Name: Phenanthro[4,3-b]thiophene
• CAS No.: 195-68-6
• Molecular Formula: C₁₆H₁₀S
• Molecular Weight: 234.321
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID40941261
• Nikkaji Number: J2.255.070E
• Wikidata: Q82918048
• Mol file: 195-68-6.mol

Synonyms:Phenanthro[4,3-b]thiophene;195-68-6;naphtho[2,1-g][1]benzothiole;Phenanthro(4,3-b)thiophene;benzonaphtho[2,1-d]thiophene;CCRIS 9363;SCHEMBL18740350;DTXSID40941261;tert-Butyl(dimethyl)silyl 1-[tert-butyl(dimethyl)silyl]-3-piperidinecarboxylate

Chemical Property of Phenanthro[4,3-b]thiophene

Chemical Property:

• Vapor Pressure: 1.49E-07mmHg at 25°C
• Boiling Point: 440.7°Cat760mmHg
• Flash Point: 166.1°C
• PSA: 116.62000
• Density: 1.292g/cm³
• LogP: 1.09210
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 234.05032149
• Heavy Atom Count: 17
• Complexity: 287

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC3=C2C4=C(C=C3)C=CS4

Technology Process of Phenanthro[4,3-b]thiophene

There total 9 articles about Phenanthro[4,3-b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-(2-methoxy-vinyl)-2-naphthalen-1-yl-thiophene → phenanthro[4,3-b]thiophene (195-68-6)

Guidance literature:

With methanesulfonic acid; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1002/jhet.5570420714

Reference yield: 70.0%

2-bromo-3-(2-(naphthalen-2-yl)-1-(phenylsulfonyl)ethyl)thiophene → phenanthro[4,3-b]thiophene (195-68-6)

Guidance literature:

With palladium diacetate; potassium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; at 80 - 140 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.joc.7b01813

Reference yield: 67.0%

7-[2-(2-methoxy-vinyl)-phenyl]-benzo[b]thiophene → phenanthro[4,3-b]thiophene (195-68-6)

Guidance literature:

With methanesulfonic acid; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1002/jhet.5570420714

upstream raw materials:

phenanthro[4,3-b]thiophene-4,5-dicarboxylic acid-anhydride

3-<β-(2-naphthyl)vinyl>thiophene

7-(2-formylphenyl)benzo[b]thiophene

7-bromobenzo(b)thiophene

Refernces

• 1、 Kumar, Subodh,Saravanan, Srinivasan,Reuben, Peter,Kumar, Atul. "Synthesis of trans-dihydrodiol derivatives of phenanthro[3,4-b]-thiophene and phenanthro[4,3-b]thiophene". . p. 1345 - 1355. Retrieved 2007/10/03.