Benzaldehyde, 2-benzo[b]thien-7-yl-

Base Information

• Chemical Name: Benzaldehyde, 2-benzo[b]thien-7-yl-
• CAS No.: 874142-91-3
• Molecular Formula: C15H10OS
• Molecular Weight: 238.31
• Mol file: 874142-91-3.mol

Synonyms:

Chemical Property of Benzaldehyde, 2-benzo[b]thien-7-yl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzaldehyde, 2-benzo[b]thien-7-yl-

There total 1 articles about Benzaldehyde, 2-benzo[b]thien-7-yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

7-bromobenzo(b)thiophene (1423-61-6) + 2-formylbenzene boronic acid (40138-16-7) → 7-(2-formylphenyl)benzo[b]thiophene (874142-91-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; In dichloromethane; for 20h; Heating;

DOI:10.1002/jhet.5570420714

Reference yield: 58.0%

7-(2-formylphenyl)benzo[b]thiophene (874142-91-3) + (methoxymethyl)triphenylphosphonium chloride (4009-98-7) → 7-[2-(2-methoxy-vinyl)-phenyl]-benzo[b]thiophene

Guidance literature:

(methoxymethyl)triphenylphosphonium chloride; With potassium tert-butylate; In tetrahydrofuran; for 0.5h;

7-(2-formylphenyl)benzo[b]thiophene; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/jhet.5570420714

Reference yield:

7-(2-formylphenyl)benzo[b]thiophene (874142-91-3) → phenanthro[4,3-b]thiophene (195-68-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium tert-butoxide / tetrahydrofuran / 0.5 h

1.2: 58 percent / tetrahydrofuran / 1 h / 20 °C

2.1: 67 percent / MeSO₃H / CH₂Cl₂ / 2 h / 0 °C

With methanesulfonic acid; potassium tert-butylate; In tetrahydrofuran; dichloromethane; 1.2: Wittig reaction;

DOI:10.1002/jhet.5570420714

upstream raw materials:

7-bromobenzo(b)thiophene

2-formylbenzene boronic acid

Downstream raw materials:

phenanthro[4,3-b]thiophene

Refernces