Benzene, 1-methyl-2-(2-phenylethenyl)-, (Z)-

Base Information

• Chemical Name: Benzene, 1-methyl-2-(2-phenylethenyl)-, (Z)-
• CAS No.: 53423-25-9
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Mol file: 53423-25-9.mol

Synonyms:

Chemical Property of Benzene, 1-methyl-2-(2-phenylethenyl)-, (Z)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-methyl-2-(2-phenylethenyl)-, (Z)-

There total 202 articles about Benzene, 1-methyl-2-(2-phenylethenyl)-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-phenylethynyltoluene (14309-60-5) → (E)-1-methyl-2-styryl-benzene (53423-25-9,74685-42-0,22257-16-5)

Guidance literature:

With formic acid; (1,2-dimethoxyethane)dichloronickel(II); zinc; bis(2-diphenylphosphinoethyl)phenylphosphine; In 1,4-dioxane; at 140 ℃; for 16h; stereoselective reaction; Sealed tube;

DOI:10.1021/acs.joc.5b01047

Reference yield: 98.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 2-methylphenyl bromide (95-46-5) → (E)-1-methyl-2-styryl-benzene (53423-25-9,74685-42-0,22257-16-5)

Guidance literature:

With C₃₄H₂₆Cl₂N₁₀Pd; tetrabutylammomium bromide; sodium acetate; at 120 ℃; for 12h;

DOI:10.1016/j.jorganchem.2019.04.009

Reference yield: 98.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + ortho-methylphenyl iodide (615-37-2) → (E)-1-methyl-2-styryl-benzene (53423-25-9,74685-42-0,22257-16-5)

Guidance literature:

With lithium hydroxide monohydrate; [N-((pyridin-2-ylmethyl)carbamothioyl)benzamide]; palladium diacetate; In N,N-dimethyl-formamide; at 120 ℃; for 10h;

DOI:10.1016/j.tetlet.2014.09.053

upstream raw materials:

2-o-tolyl-2-phenylethanol

1-methyl-2-vinyl-benzene

benzene

styrene

Downstream raw materials:

1-methyl-2-phenethylbenzene

(+/-)-erythro-α,α'-dibromo-2-methyl-bibenzyl

α,α'-dibromo-2-methyl-bibenzyl

(E)-1-methyl-2-styryl-benzene

Refernces

• 1、 Baweja, Saral,Clauss, Reike,Gelman, Dmitri,Hey-Hawkins, Evamarie. "Heterobimetallic Pd/Mn and Pd/Co complexes as efficient and stereoselective catalysts for sequential Cu-free Sonogashira coupling–alkyne semi-hydrogenation reactions". . p. 1344 - 1356. Retrieved 2022/02/03.
• 2、 Patil, Vijay P,Kashid, Abhijit A,Solanki, Bhanupratap S,Kharul, Ulhas K,Iyer, Suresh. "Bimetallic nano alloy architecture on a special polymer: Ni or Cu merged with Pd for the promotion of the Mizoroki–Heck reaction and the Suzuki–Miyaura coupling". . . Retrieved 2021/02/12.