Technology Process of 2-Propenoic acid, 3-[2-bromo-4-(1,1-dimethylethyl)phenyl]-, (2E)-
There total 5 articles about 2-Propenoic acid, 3-[2-bromo-4-(1,1-dimethylethyl)phenyl]-, (2E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
methanol;
for 3h;
Heating;
DOI:10.1021/jm049485i
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 100 percent / NaBrO3; aq. NaHSO3 / acetonitrile / 6 h
2.1: 94 percent / NaOEt; EtOH; 2-nitropropane / 5 h / 25 °C
3.1: NaH / tetrahydrofuran / 0.5 h / 20 °C
3.2: tetrahydrofuran / 3 h / Heating
4.1: 4.3 g / aq. NaOH / methanol / 3 h / Heating
With
sodium hydroxide; sodium bromate; ethanol; 2-nitropropane; sodium ethanolate; sodium hydride; sodium hydrogensulfite;
In
tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/jm049485i
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 94 percent / NaOEt; EtOH; 2-nitropropane / 5 h / 25 °C
2.1: NaH / tetrahydrofuran / 0.5 h / 20 °C
2.2: tetrahydrofuran / 3 h / Heating
3.1: 4.3 g / aq. NaOH / methanol / 3 h / Heating
With
sodium hydroxide; ethanol; 2-nitropropane; sodium ethanolate; sodium hydride;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm049485i
