5,6-Dihydro-2-methyl-2H-pyran

Base Information

• Chemical Name: 5,6-Dihydro-2-methyl-2H-pyran
• CAS No.: 55230-25-6
• Molecular Formula: C6H10O
• Molecular Weight: 98.1448
• Hs Code.: 2932999099
• Mol file: 55230-25-6.mol

Synonyms:2-methyl-5,6-dihydro-2H-pyran;2H-Pyran,5,6-dihydro-2-methyl;

Chemical Property of 5,6-Dihydro-2-methyl-2H-pyran

Chemical Property:

• Vapor Pressure: 22.3mmHg at 25°C
• Boiling Point: 115.8oC at 760 mmHg
• Flash Point: 10.5oC
• PSA: 9.23000
• Density: 0.885g/cm3
• LogP: 1.35140

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-Dihydro-2-methyl-2H-pyran

There total 13 articles about 5,6-Dihydro-2-methyl-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-methoxy-3,6-dihydro-2H-pyran (6559-34-8) + methylmagnesium bromide (75-16-1) → 4-methyl-3,4-dihydro-2H-pyran (2270-61-3) + 6-methyl-3,6-dihydro-2H-pyran (55230-25-6)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; at 80 ℃; for 4h;

DOI:10.1016/S0040-4039(98)00162-2

Reference yield: 50.6%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + penta-1,3-diene (504-60-9,17410-45-6,25212-15-1,64940-84-7) → 6-methyl-3,6-dihydro-2H-pyran (55230-25-6)

Guidance literature:

In tetrahydrofuran; at 240 ℃; for 6h; Autoclave;

Reference yield: 17.0%

4-propenyl-1,3-dioxane (40749-83-5) → 6-methyl-3,6-dihydro-2H-pyran (55230-25-6) + 1,3,5-hexatriene (2235-12-3) + 2,4-hexadien-1-ol acetate (1516-17-2) + 3,5-hexadien-1-ol acetate (75338-23-7)

Guidance literature:

With sulfuric acid; In ethyl acetate; at 90 ℃; for 9h; Further byproducts given; metal ampul;

upstream raw materials:

2-hydroxy-2-methyltetrahydropyran

cis-3-chloro-2-methyltetrahydropyran

formaldehyd

penta-1,3-diene

Downstream raw materials:

(+/-)-c-2-methyltetrahydropyran-r-3,t-4-diol

2-dichloromethyl-2-methyl-5,6-dihydro-2H-pyran

2,3-Epoxy-2-methyl-tetrahydro-pyran

2-hydroxy-2-methyltetrahydropyran

Refernces

• 1、 -. "A dihydro maltol and dihydro ethyl maltol synthetic method". Paragraph 0021; 0022; 0023. . Retrieved 2017/08/25.
• 2、 Guagnano, Vito,Lardicci, Luciano,Malanga, Corrado,Menicagli, Rita. "Regioselective Ni(II)-assisted alkylation of 2-methoxy-5,6- dihydro-2H-pyran: A new route to 2-n.alkyl-5,6-dihydro-2H-pyrans". . p. 2025 - 2026. Retrieved 2007/10/03.