M-T-BUTYLPHENYLBORONIC ACID

Base Information

• Chemical Name: M-T-BUTYLPHENYLBORONIC ACID
• CAS No.: 560132-24-3
• Molecular Formula: C10H15BO2
• Molecular Weight: 178.12
• Hs Code.: 2931900090
• Mol file: 560132-24-3.mol

Synonyms:m-T-Butylphenylboronic acid;

Chemical Property of M-T-BUTYLPHENYLBORONIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 221 °C(Solv: water (7732-18-5))
• Refractive Index: 1.511
• Boiling Point: 304.35 °C at 760 mmHg
• PKA: 8?+-.0.10(Predicted)
• Flash Point: 137.866 °C
• PSA: 40.46000
• Density: 1.029 g/cm³
• LogP: 0.66390
• Storage Temp.: Room temperature.

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-tert-ButylphenylboronicAcid ^*data from reagent suppliers

Safty Information:

• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of M-T-BUTYLPHENYLBORONIC ACID

There total 1 articles about M-T-BUTYLPHENYLBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

Trimethyl borate (121-43-7,63156-11-6) + 1-bromo-3-(tertbutyl)benzene (3972-64-3) → 3-tert-butylphenylboronic acid (560132-24-3)

Guidance literature:

1-bromo-3-(tertbutyl)benzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃;

With hydrogenchloride; In water; at 20 ℃; for 0.5h;

DOI:10.1002/anie.201805063

Reference yield: 99.2%

N-(2-cyanophenyl)benzamide (40288-69-5) + 3-tert-butylphenylboronic acid (560132-24-3) → 4-(4-(tert-butyl)phenyl)-2-phenylquinazoline

Guidance literature:

With [2,2]bipyridinyl; palladium diacetate; trifluoroacetic acid; In tetrahydrofuran; at 90 ℃; for 16h; Reagent/catalyst; Solvent; Catalytic behavior;

Reference yield: 91.0%

4-amino-3,5-dibromopyridine (84539-34-4) + 3-tert-butylphenylboronic acid (560132-24-3) → 3,5-di-(3-tert-butyl-phenyl)-4-aminopyridine

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; for 16h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.202004983

upstream raw materials:

Trimethyl borate

1-bromo-3-(tertbutyl)benzene

Downstream raw materials:

6-(3-(tert-butyl)phenyl)-3-(pyridin-4-yl)imidazo[1,2-b]pyridazine

6-(3-(tert-butyl)phenyl)-3-(4-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazine

(S)-(3’-tert-butyl-[1,1’-biphenyl]-4-yl)methyl 2-(((S)-3-amino-1-cyano-3-oxopropyl)carbamoyl)-pyrrolidine-1-carboxylate

Refernces

• 1、 -. "Organic electroluminescent materials and devices". Page/Page column 102; 103. . Retrieved 2016/04/20.
• 2、 -. "Phosphorescent condensed ring carbene metal complexes for use in organic light emitting devices". . . Retrieved 2010/11/04.