Technology Process of 4-(Chloromethyl)quinoline
There total 17 articles about 4-(Chloromethyl)quinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
thionyl chloride;
In
dichloromethane;
at 20 ℃;
for 5h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: methanol; sodium tetrahydroborate / 1.33 h / 0 - 20 °C
2.1: thionyl chloride / dichloromethane / 2.33 h / 0 - 20 °C
2.2: pH > 7 / Saturated solution
With
methanol; sodium tetrahydroborate; thionyl chloride;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 °C
2: thionyl chloride / dichloromethane / 2 h / 0 - 20 °C
With
lithium aluminium tetrahydride; thionyl chloride;
In
tetrahydrofuran; dichloromethane;
