Technology Process of 4-(Bromomethyl)quinoline
There total 11 articles about 4-(Bromomethyl)quinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrachloromethane; N-Bromosuccinimide; dibenzoyl peroxide;
DOI:10.1021/ja01176a096
- Guidance literature:
-
With
hydrogen bromide;
at 140 ℃;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-bromo-succinimide; dibenzoyl peroxide; tetrachloromethane
2: sodium acetate; acetic acid
3: sodium acetate / 130 °C
4: phosphoryl chloride
5: potassium carbonate; water; ethanol
6: palladium; methanol; NaOH-solution / Hydrogenation
7: aqueous hydrobromic acid / 140 °C
With
methanol; tetrachloromethane; sodium hydroxide; N-Bromosuccinimide; ethanol; water; hydrogen bromide; sodium acetate; potassium carbonate; palladium; acetic acid; trichlorophosphate; dibenzoyl peroxide;