N-ETHYL-6-BROMO-CARBAZOLE

Base Information

• Chemical Name: N-ETHYL-6-BROMO-CARBAZOLE
• CAS No.: 57102-97-3
• Molecular Formula: C14H12BrN
• Molecular Weight: 274.16
• Hs Code.: 2933990090
• Mol file: 57102-97-3.mol

Synonyms:3-bromo-9-ethylcarbazole;

Chemical Property of N-ETHYL-6-BROMO-CARBAZOLE

Chemical Property:

• Vapor Pressure: 1.39E-06mmHg at 25°C
• Melting Point: 82.0 to 86.0 °C
• Boiling Point: 399.2oC at 760 mmHg
• Flash Point: 195.2oC
• PSA: 4.93000
• Density: 1.4g/cm3
• LogP: 4.57690
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Toluene

Purity/Quality:

99% ^*data from raw suppliers

3-Bromo-9-ethylcarbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ETHYL-6-BROMO-CARBAZOLE

There total 2 articles about N-ETHYL-6-BROMO-CARBAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethylcarbazole (86-28-2) → 3-bromo-9-ethyl-9H-carbazole (57102-97-3) + 3,6-dibromo-9-ethyl-9H-carbazole (33255-13-9)

Guidance literature:

With potassium bromate; hydrogenchloride; acetic acid; potassium bromide;

Reference yield:

N-ethylcarbazole (86-28-2) → 3-bromo-9-ethyl-9H-carbazole (57102-97-3) + 3,6-dibromo-9-ethyl-9H-carbazole (33255-13-9) + 9-ethyl-1,3,6-trisbromocarbazole (144434-81-1)

Guidance literature:

With N-Bromosuccinimide; silica gel; In dichloromethane; at 18 ℃; for 6h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4020(01)90362-X

Reference yield: 89.0%

3-bromo-9-ethyl-9H-carbazole (57102-97-3) + 1-((4-methoxyphenyl)(tosyl)methyl)naphthalen-2-ol → 1-((9-ethyl-9H-carbazol-3-yl)(4-methoxyphenyl)methyl)naphthalen-2-ol

Guidance literature:

3-bromo-9-ethyl-9H-carbazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Schlenk technique; Inert atmosphere;

With zinc dibromide; In tetrahydrofuran; hexane; at 0 ℃; for 0.25h; Schlenk technique; Inert atmosphere;

1-((4-methoxyphenyl)(tosyl)methyl)naphthalen-2-ol; In tetrahydrofuran; hexane; at 60 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.joc.8b01428

upstream raw materials:

N-ethylcarbazole

Downstream raw materials:

9-ethyl-3-triphenylsilanyl-carbazole

tris-(9-ethyl-carbazol-3-yl)-phenyl-silane

bis-(9-ethyl-carbazol-3-yl)-diphenyl-silane

9-Ethyl-9H-carbazole-3-carboxylic acid

Refernces