3-(Phosphono)pyruvic acid

Base Information

• Chemical Name: 3-(Phosphono)pyruvic acid
• CAS No.: 5824-58-8
• Molecular Formula: C3H5O6P
• Molecular Weight: 168.043
• Hs Code.: 2931900090
• Mol file: 5824-58-8.mol

Synonyms:Propanoic acid,2-oxo-3-phosphono;PHOSPHONOPYRUVATE;1kc7;phosphonopyruvic acid;

Chemical Property of 3-(Phosphono)pyruvic acid

Chemical Property:

• PSA: 121.71000
• LogP: -1.18220

Purity/Quality:

99%, ^*data from raw suppliers

3-PHOSPHONO PYRUVIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A novel carbon-phosphorus bond cleavage enzyme from Variovorax sp. Pal2.

Technology Process of 3-(Phosphono)pyruvic acid

There total 3 articles about 3-(Phosphono)pyruvic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoenolpyruvic acid (138-08-9) + phosphonopyruvate decarcoxylase + phosphonoenolpyruvate phosphomutase → 3‐phosphopyruvate (5824-58-8)

Guidance literature:

With thiamine diphosphate; magnesium sulfate; In various solvent(s); at 30 ℃; for 7h; pH=7.5; Enzymatic reaction; initial compound concentration 1, 10, 50 and 100 mM; reaction was carried out in Tris-HCl buffer;

DOI:10.7164/antibiotics.50.212

Reference yield:

phosphonopyruvate triethylammonium salt → 3‐phosphopyruvate (5824-58-8)

Guidance literature:

With Dowex-50 (H+); In water;

Reference yield:

DL-2-amino-3-phosphonopropionic acid (5652-28-8) → 3‐phosphopyruvate (5824-58-8)

Guidance literature:

DOI:10.7164/antibiotics.50.212

upstream raw materials:

phosphoenolpyruvic acid

DL-2-amino-3-phosphonopropionic acid

Downstream raw materials:

phosphonoacetalhdehyde

sodium pyruvate

phosphoenolpyruvic acid

Refernces

• 1、 Freeman, Sally,Irwin, William J.,Schwalbe, Carl H.. "Synthesis and Hydrolysis Studies of Phosphonopyruvate". . p. 263 - 267. Retrieved 2007/10/02.