Technology Process of o-(4-Diethylamino-2-methoxybenzoyl)benzoic acid
There total 1 articles about o-(4-Diethylamino-2-methoxybenzoyl)benzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
phthalic anhydride; N,N-diethyl-3-methoxyaniline;
With
aluminum (III) chloride;
In
dichloromethane;
at 0 ℃;
for 4h;
Inert atmosphere;
With
hydrogenchloride; water;
In
dichloromethane;
for 0.166667h;
Inert atmosphere;
DOI:10.1039/c0cc03407j
- Guidance literature:
-
4-diethylamino-2-methoxy-2'-carboxybenzophenone;
With
boron tribromide;
In
dichloromethane;
at -78 - -25 ℃;
With
water;
In
dichloromethane;
DOI:10.1039/c0cc03407j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: boron tribromide / dichloromethane / -78 - -25 °C
2.1: methanesulfonic acid / 2 h / 90 °C / Sealed tube
2.2: 0.33 h / pH 11 - 12 / Cooling with ice
3.1: trifluoroacetic acid / tetrahydrofuran
With
methanesulfonic acid; boron tribromide; trifluoroacetic acid;
In
tetrahydrofuran; dichloromethane;
