alpha-methylphenethylamine

Base Information

• Chemical Name: alpha-methylphenethylamine
• CAS No.: 60-15-1
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.209
• Mol file: 60-15-1.mol

Synonyms:2-Aminopropylbenzene;3-Phenyl-2-propylamine;3-Phenyl-2-propanamine;1-Phenyl-2-propanamine;

Chemical Property of alpha-methylphenethylamine

Chemical Property:

• Vapor Pressure: 0.0521mmHg at 25°C
• Boiling Point: 234.7oC at 760 mmHg
• Flash Point: 98.7oC
• PSA: 26.02000
• Density: 0.958g/cm3
• LogP: 2.27660

Purity/Quality:

99.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-methylphenethylamine

There total 95 articles about alpha-methylphenethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methyl-5-phenyl-2-oxazolidinone (54418-69-8) → 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2)

Guidance literature:

With 5% Pd(II)/C(eggshell); hydrogen; In tetrahydrofuran; at 20 ℃; for 3h; under 1 Torr;

DOI:10.1080/00397910903097302

Reference yield: 96.0%

2-methyl-3-phenylaziridine → 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 16h; under 760.051 Torr; Inert atmosphere;

Reference yield: 91.0%

(2-nitroprop-1-enyl)benzene (705-60-2) → 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2)

Guidance literature:

With sodium tetrahydroborate; borane-THF; In tetrahydrofuran; at 25 ℃; for 144h;

DOI:10.1016/S0040-4020(01)89059-1

upstream raw materials:

(E)-2-(hydroxyimino)-1-phenylpropan-1-one

l-amphetamine

(1-phenylpropan-2-ylidene)hydrazine

2-methyl-2-phenylpropionamide

Downstream raw materials:

bis-(2-hydroxy-ethyl)-(1-methyl-2-phenyl-ethyl)-amine

2-(1-methyl-2-phenyl-ethylamino)-ethanol

N-(1-Methyl-2-phenyl-ethyl)-β-mercapto-ethylamin

N-(1-methyl-2-phenyl-ethyl)-ethylenediamine

Refernces

• 1、 -. "ASPARAGINE DERIVATIVES AND METHODS OF USE THEREOF". . . Retrieved 2021/12/31.
• 2、 Basso, Ernani A.,Fernandes, Cleverton de S.,Francisco, Camila B.,Gauze, Gisele de F.,Rittner, Roberto. "Rapid Synthesis of Primary Amines from Ketones using Choline Chloride/Urea Deep Eutectic as a Reaction Medium". . . Retrieved 2021/12/29.