2-(α-Methylphenethyl)aminoethanol

Base Information

• Chemical Name: 2-(α-Methylphenethyl)aminoethanol
• CAS No.: 63918-85-4
• Molecular Formula: C11H17 N O
• Molecular Weight: 179.29
• Hs Code.: 2922199090
• Mol file: 63918-85-4.mol

Synonyms:Ethanol,2-[(a-methylphenethyl)amino]- (6CI);2-(1-Methyl-2-phenethylamino)ethanol

Chemical Property of 2-(α-Methylphenethyl)aminoethanol

Chemical Property:

• Vapor Pressure: 0.000267mmHg at 25°C
• Refractive Index: 1.5320 (estimate)
• Boiling Point: 309.9°Cat760mmHg
• Flash Point: 116.8°C
• PSA: 32.26000
• Density: 1.004g/cm³
• LogP: 1.59040

Purity/Quality:

99% ^*data from raw suppliers

2-[(1-PHENYLPROPAN-2-YL)AMINO]ETHAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(α-Methylphenethyl)aminoethanol

There total 2 articles about 2-(α-Methylphenethyl)aminoethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

ethanolamine (141-43-5) + 1-phenyl-acetone (103-79-7,136675-26-8) → 2-(1-methyl-2-phenyl-ethylamino)-ethanol (63918-85-4)

Guidance literature:

ethanolamine; 1-phenyl-acetone; With titanium(IV) isopropylate; In methanol; at 20 ℃;

With sodium tetrahydroborate; In methanol; at 0 ℃; for 2h; Further stages.;

DOI:10.1016/j.tet.2008.02.055

Reference yield:

oxirane (75-21-8,99932-75-9) + 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2) → 2-(1-methyl-2-phenyl-ethylamino)-ethanol (63918-85-4)

Guidance literature:

Reference yield:

2-(1-methyl-2-phenyl-ethylamino)-ethanol (63918-85-4) → (2-chloro-ethyl)-isobutyl-(1-methyl-2-phenyl-ethyl)-amine

Guidance literature:

Multi-step reaction with 2 steps

2: CHCl₃; SOCl₂

With thionyl chloride; chloroform;

DOI:10.1021/ja01165a042

upstream raw materials:

oxirane

2-amino-1-phenylpropane

ethanolamine

1-phenyl-acetone

Downstream raw materials:

2-{[2-(2-benzyl-phenoxy)-ethyl]-(1-methyl-2-phenyl-ethyl)-amino}-ethanol

N-(α-Methylphenethyl)-N-<2-(o-benzoylphenoxy)ethyl>-p-toluenesulfonamide

SKF 502

Refernces