Phenol, 2-[(2-furanylmethylene)amino]-

Base Information

• Chemical Name: Phenol, 2-[(2-furanylmethylene)amino]-
• CAS No.: 6078-02-0
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.198
• DSSTox Substance ID: DTXSID40473077
• Nikkaji Number: J1.831.048A,J877.008E
• Mol file: 6078-02-0.mol

Synonyms:6078-02-0;Phenol, 2-[(2-furanylmethylene)amino]-;furfurylideneaminophenol;DTXSID40473077

Chemical Property of Phenol, 2-[(2-furanylmethylene)amino]-

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 187.063328530
• Heavy Atom Count: 14
• Complexity: 206

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N=CC2=CC=CO2)O

Technology Process of Phenol, 2-[(2-furanylmethylene)amino]-

There total 4 articles about Phenol, 2-[(2-furanylmethylene)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

furfural (98-01-1) + 2-amino-phenol (95-55-6) → 2-(furan-2-ylmethylene)aminophenol (6078-02-0)

Guidance literature:

In neat (no solvent, solid phase); for 0.166667 - 0.25h;

DOI:10.1016/j.ica.2018.12.028

Reference yield: 77.0%

furfural (98-01-1) + 2-amino-phenol (95-55-6) → 2-furfurylideneamino-phenol (6078-02-0)

Guidance literature:

With acetic acid; In ethanol; for 3h; Reflux;

DOI:10.3390/molecules26175164

Reference yield:

2-furfurylideneamino-phenol (6078-02-0) → 2-(furan-2-yl)benzoxazole (881-60-7) + 2-Furan-2-yl-2,3-dihydro-benzooxazole + cis-N-(2-Furanylmethylene)-o-aminophenol (6078-02-0)

Guidance literature:

In methyl cyclohexane; Title compound not separated from byproducts; Ambient temperature; Irradiation;

DOI:10.1021/jo00334a029

upstream raw materials:

furfural

2-amino-phenol

Downstream raw materials:

2-(furan-2-yl)benzoxazole

Refernces

• 1、 Almarhoon, Zainab M.,Garcia, Yann,Lakbaibi, Zouhair,Mabkhot, Yahia N.,Radi, Smaail,Roby, Othmane,Saddik, Rafik,Tighadouini, Said. "A highly efficient environmental-friendly adsorbent based on schiff base for removal of cu(Ii) from aqueous solutions: A combined experimental and theoretical study". . . Retrieved 2021/09/04.
• 2、 Li, Fengxi,Li, Zhengqiang,Tang, Xuyong,Cao, Xinyu,Wang, Chunyu,Li, Jialin,Wang, Lei. "Hemoglobin: A New Biocatalyst for the Synthesis of 2-substituted Benzoxazoles via Oxidative Cyclization". . p. 1192 - 1195. Retrieved 2019/02/07.