3-methyl-3-phenyl-butanal

Base Information

• Chemical Name: 3-methyl-3-phenyl-butanal
• CAS No.: 6325-41-3
• Molecular Formula: C11H14O
• Molecular Weight: 162.232
• Hs Code.: 2912299000
• Mol file: 6325-41-3.mol

Synonyms:3-methyl-3-phenyl-butyraldehyde;Cumylacetaldehyde;3-Methyl-3-phenyl-butyraldehyd;3-methyl-3-phenyl-butanal;3,3-dimethyl-3-phenylpropionaldehyde;

Chemical Property of 3-methyl-3-phenyl-butanal

Chemical Property:

• Vapor Pressure: 0.0794mmHg at 25°C
• Boiling Point: 227°Cat760mmHg
• Flash Point: 94.5°C
• PSA: 17.07000
• Density: 0.954g/cm³
• LogP: 2.55320
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

3-Methyl-3-phenylbutyraldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methyl-3-phenyl-butanal

There total 16 articles about 3-methyl-3-phenyl-butanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

→ 3-methyl-3-phenylbutanal (6325-41-3)

Guidance literature:

In benzene; at 100 ℃; for 12h;

DOI:10.1021/ja9714999

Reference yield: 46.0%

→ 3-methyl-3-phenylbutanal (6325-41-3) + 3-methyl-3-phenylbutan-1-ol (21438-74-4)

Guidance literature:

at 100 ℃; for 48h;

DOI:10.1021/ja9714999

Reference yield: 12.0%

diphenylantimony(III) chloride (2629-47-2) + 3-methyl-2-buten-1-ol (556-82-1) → biphenyl (92-52-4,1594-86-1) + 3-methyl-3-phenylbutanal (6325-41-3)

Guidance literature:

With palladium diacetate; In acetonitrile; at 25 ℃; for 24h; Yields of byproduct given;

DOI:10.1016/S0022-328X(98)00974-7

upstream raw materials:

chloroform

neophyl chloride

orthoformic acid triethyl ester

2-methyl-2-phenyl-1-propylmagnesium chloride

Downstream raw materials:

tert-butylbenzene

1-phenyl-2-methylpropane

3-methyl-3-phenyl-butyryl chloride

3-methyl-3-phenyl-butyraldehyde-semicarbazone

Refernces

• 1、 Ezawa, Masatoshi,Togo, Hideo. "One-Pot Preparation of C1-Homologated Aliphatic Nitriles from Aldehydes through a Wittig Reaction under Metal-Cyanide-Free Conditions". . p. 2379 - 2384. Retrieved 2017/05/01.
• 2、 Harada, Nari-Aki,Nishikata, Takashi,Nagashima, Hideo. "Vinyl polymerization versus [1,3] O to C rearrangement in the ruthenium-catalyzed reactions of vinyl ethers with hydrosilanes". . p. 3243 - 3252. Retrieved 2012/06/01.