4-Hydroxybenzoic acid hexadecyl ester

Base Information

• Chemical Name: 4-Hydroxybenzoic acid hexadecyl ester
• CAS No.: 71067-09-9
• Molecular Formula: C23H38O3
• Molecular Weight: 362.553
• Mol file: 71067-09-9.mol

Synonyms:hexadecyl 4-hydroxybenzoate;

Chemical Property of 4-Hydroxybenzoic acid hexadecyl ester

Chemical Property:

• Vapor Pressure: 1.1E-09mmHg at 25°C
• Melting Point: 52.5-53.0 °C
• Refractive Index: 1.497
• Boiling Point: 476 °C at 760 mmHg
• PKA: 8.22±0.15(Predicted)
• Flash Point: 179.9 °C
• PSA: 46.53000
• Density: 0.971 g/cm³
• LogP: 7.03030
• Water Solubility.: 378.9mg/L(25 oC)

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxybenzoic acid hexadecyl ester

There total 2 articles about 4-Hydroxybenzoic acid hexadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.9%

1-Hexadecanol (36653-82-4,124-29-8) + 4-hydroxy-benzoic acid (99-96-7) → hexadecyl 4-hydroxybenzoate (71067-09-9)

Guidance literature:

With [HBth]H₂PW₁₂O₄₀; In toluene; at 105 ℃; for 8h; Green chemistry;

DOI:10.1134/S1070428020050205

Reference yield:

1-Hexadecanol (36653-82-4,124-29-8) + methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → hexadecyl 4-hydroxybenzoate (71067-09-9)

Guidance literature:

With titanium(IV) isopropylate; at 70 - 160 ℃; for 1h; Dean-Stark;

Reference yield: 100.0%

hexadecyl 4-hydroxybenzoate (71067-09-9) + 4-(3-bromopropoxy)-3-methoxybenzaldehyde (148433-00-5) → cetyl 4-[3-(4-formyl-2-methoxyphenoxy)propoxy]benzoate

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1039/d1nj03830c

upstream raw materials:

1-Hexadecanol

methyl 4-hydroxylbenzoate

4-hydroxy-benzoic acid

Downstream raw materials:

3,3'-thiobis(hexadecyl p-hydroxybenzoate)

Refernces

• 1、 -. "INSECT PEST REPELLENT". Paragraph 0032; 0033; 0034. . Retrieved 2020/01/24.