TRANS-1,3-DIPHENYL-2-PROPEN-1-OL

Base Information

• Chemical Name: TRANS-1,3-DIPHENYL-2-PROPEN-1-OL
• CAS No.: 62668-02-4
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Hs Code.: 2906299090
• Mol file: 62668-02-4.mol

Synonyms:3,3-Diphenylprop-2-en-1-ol;

Chemical Property of TRANS-1,3-DIPHENYL-2-PROPEN-1-OL

Chemical Property:

• Melting Point: 55-57oC
• Boiling Point: 368.471 °C at 760 mmHg
• PKA: 13.80±0.20(Predicted)
• Flash Point: 160.31 °C
• PSA: 20.23000
• Density: 1.11 g/cm³
• LogP: 3.11060
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

trans-1,3-Diphenyl-2-propen-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: trans-1,3-diphenyl-2-propen-1-ol may be used as a model substrate to investigate the formation of substituted cyclopropanes by SiO2-ZrO2 mixed oxides catalyzed Friedel-Crafts-alkylation followed by trans-hydrogenation.

Technology Process of TRANS-1,3-DIPHENYL-2-PROPEN-1-OL

There total 115 articles about TRANS-1,3-DIPHENYL-2-PROPEN-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzalacetophenone (94-41-7) → 1,3-diphenyl-3-hydroxypropene (4663-33-6,62668-02-4,62839-70-7,116127-91-4,132014-29-0,136981-81-2,148616-45-9)

Guidance literature:

With silica gel; sodium cyanoborohydride; for 0.0208333h; regioselective reaction; Neat (no solvent); Microwave irradiation;

DOI:10.5012/bkcs.2010.31.10.2961

Reference yield: 99.0%

(E)-3-phenylpropenal (14371-10-9) + bromobenzene (108-86-1,52753-63-6) → (E)-1,3-diphenyl-2-propen-1-ol (62668-02-4)

Guidance literature:

With iodine; magnesium; In tetrahydrofuran; 1.) reflux; 2.) 20 deg C then 22 deg C;

DOI:10.1016/0040-4020(95)00659-V

Reference yield: 99.0%

rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene (87751-69-7) → (E)-1,3-diphenyl-2-propen-1-ol (62668-02-4)

Guidance literature:

With cetyltrimethylammonium hydroxide; malonic acid dimethyl ester; (R)-(+)-2,2’-bis(diphenylphosphino)-1,1’-binaphthalene; bis(η3-allyl-μ-chloropalladium(II)); In water; at 25 ℃; for 1h;

DOI:10.1002/adsc.200390040

upstream raw materials:

aluminum ethoxide

benzalacetophenone

3-bromro-1,3-diphenyl-1-propene

trans-1-benzylsulfonyl-2-phenylethene

Downstream raw materials:

(3-methoxyprop-1-ene-1,3-diyl)dibenzene

(E)-1,3-diphenyl-3-chloroprop-1-ene

1,3-diphenyl-propen-3-one

ethyl (E)-1,3-diphenyl-2-propen-1-yl carbonate

Refernces

• 1、 Sinou, Denis,Rabeyrin, Cedric,Nguefack, Christelle. "Catalytic Asymmetric Alkylation in Water in the Presence of Surfactants". . p. 357 - 363. Retrieved 2003.
• 2、 Singh, Bara,Bankar, Siddheshwar K.,Ramasastry. "Pd-Catalyzed Nazarov-Type Cyclization: Application in the Total Synthesis of β-Diasarone and Other Complex Cyclopentanoids". supporting information. p. 1043 - 1048. Retrieved 2022/02/05.
• 3、 Ai, Jing-Jing,Li, Jian,Ji, Shun-Jun,Wang, Shun-Yi. "One-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions: Atom-economic synthesis of selenocarbamates and allyl sulfones". supporting information. p. 721 - 724. Retrieved 2020/07/24.