1-BROMO-4-BUTOXYBENZENE

Base Information

• Chemical Name: 1-BROMO-4-BUTOXYBENZENE
• CAS No.: 39969-57-8
• Molecular Formula: C10H13BrO
• Molecular Weight: 229.117
• Hs Code.: 2909309090
• Mol file: 39969-57-8.mol

Synonyms:Ether,p-bromophenyl butyl (6CI);1-Bromo-4-butoxybenzene;4-Bromo-1-butoxybenzene;4-Bromo-n-butoxybenzene;4-Bromophenyl butyl ether;4-Butoxy-1-bromobenzene;4-Butoxybromobenzene;4-Butoxyphenyl bromide;NSC 406732;p-Bromobutoxybenzene;p-Butoxybromobenzene;

Chemical Property of 1-BROMO-4-BUTOXYBENZENE

Chemical Property:

• Vapor Pressure: 0.0163mmHg at 25°C
• Melting Point: 79-80 °C
• Refractive Index: 1.52
• Boiling Point: 263.9 °C at 760 mmHg
• Flash Point: 114.7 °C
• PSA: 9.23000
• Density: 1.278 g/cm³
• LogP: 3.62800
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

1-Bromo-4-butoxybenzene ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-BROMO-4-BUTOXYBENZENE

There total 9 articles about 1-BROMO-4-BUTOXYBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

n-butyl phenyl ether (1126-79-0) → 1-bromo-4-butoxybenzene (39969-57-8)

Guidance literature:

With aluminum oxide; sodium chlorite; water; manganese(III) acetylacetonate; sodium bromide; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1080/00304949809355283

Reference yield: 97.0%

1,4-bromoiodobenzene (589-87-7) + butan-1-ol (71-36-3) → 1-bromo-4-butoxybenzene (39969-57-8)

Guidance literature:

With copper(l) iodide; sodium t-butanolate; In N,N-dimethyl-formamide; for 24h; Schlenk technique; Inert atmosphere; Molecular sieve; Heating;

DOI:10.1021/jacs.8b12142

Reference yield: 93.0%

1-bromo-butane (109-65-9) + 4-bromo-phenol (106-41-2) → 1-bromo-4-butoxybenzene (39969-57-8)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; at 120 ℃; for 16h; under 633.813 Torr;

DOI:10.1002/chem.202004481

upstream raw materials:

1-bromo-butane

4-bromo-phenol

n-butyl phenyl ether

1-iodo-butane

Downstream raw materials:

4-butoxy-1,1’-biphenyl

2-(4-butoxyphenyl)thiophene

5-bromo-2-butoxybenzaldehyde

butoxycaine

Refernces

• 1、 Flores, J. Reyes,Castruita-De León, Griselda,Turlakov, Gleb,Arias, Eduardo,Moggio, Ivana,Montemayor, Sagrario M.,Torres, Román,Ledezma, Raquel,Ziolo, Ronald F.,González-Torres, Julio. "Dual Emission of meso-Phenyleneethynylene–BODIPY Oligomers: Synthesis, Photophysics, and Theoretical Optoelectronic Study". supporting information. p. 2493 - 2505. Retrieved 2020/12/23.
• 2、 Mills, L. Reginald,Monteith, John J.,Dos Passos Gomes, Gabriel,Aspuru-Guzik, Alán,Rousseaux, Sophie A. L.. "The Cyclopropane Ring as a Reporter of Radical Leaving-Group Reactivity for Ni-Catalyzed C(sp3)-O Arylation". supporting information. p. 13246 - 13254. Retrieved 2020/09/01.