6-Methyl-1-tetralone

Base Information

• Chemical Name: 6-Methyl-1-tetralone
• CAS No.: 51015-29-3
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Hs Code.: 2914399090
• European Community (EC) Number: 256-913-1
• UNII: HTW3PM158Y
• DSSTox Substance ID: DTXSID0068608
• Nikkaji Number: J261.611D
• Wikidata: Q27280097
• Mol file: 51015-29-3.mol

Synonyms:6-METHYL-1-TETRALONE;51015-29-3;6-methyl-3,4-dihydronaphthalen-1(2h)-one;6-methyl-3,4-dihydro-2H-naphthalen-1-one;1(2H)-Naphthalenone, 3,4-dihydro-6-methyl-;3,4-Dihydro-6-methylnaphthalen-1(2H)-one;EINECS 256-913-1;UNII-HTW3PM158Y;HTW3PM158Y;6-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE;6-methyltetralone;SCHEMBL1027718;DTXSID0068608;AM9346;MFCD00049168;AKOS006271808;CS-W004312;DS-7401;MB00436;3,4-dihydro-6-methyl-1(2h)-naphthalenon;6-methyl-3,4-dihydro-1(2H)-naphthalenone;3,4-Dihydro-6-methyl-1(2H)-naphthalenone;FT-0708870;I10918;A871397;Q27280097;3,4 - dihydro - 6 - methylnaphthalen - 1(2H) - one;F9994-5204

Chemical Property of 6-Methyl-1-tetralone

Chemical Property:

• Vapor Pressure: 0.00294mmHg at 25°C
• Refractive Index: 1.557
• Boiling Point: 284.7 °C at 760 mmHg
• Flash Point: 119.7 °C
• PSA: 17.07000
• Density: 1.074 g/cm³
• LogP: 2.51400
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 160.088815002
• Heavy Atom Count: 12
• Complexity: 185

Purity/Quality:

98%, ^*data from raw suppliers

6-METHYL-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)C(=O)CCC2
• Uses: 6-Methyl-1-tetralone is a useful reagent in Photocatalytic reactions.

Technology Process of 6-Methyl-1-tetralone

There total 42 articles about 6-Methyl-1-tetralone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(m-tolyl)butanoic acid (22156-45-2) → 6-methyl-3,4-dihydronaphthalen-1(2H)-one (51015-29-3)

Guidance literature:

With trifluorormethanesulfonic acid; at 5 - 20 ℃; for 2h;

DOI:10.1002/(SICI)1521-3773(19990802)38:15<2267::AID-ANIE2267>3.0.CO;2-3

Reference yield: 96.0%

tetramethylstannane (594-27-4) + 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate (144464-64-2) → 6-methyl-3,4-dihydronaphthalen-1(2H)-one (51015-29-3)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; 2,6-di-tert-butyl-4-methyl-phenol; lithium chloride; In N,N-dimethyl-formamide; at 90 ℃; for 18h; Inert atmosphere;

DOI:10.1002/chem.201406133

Reference yield: 92.0%

4-(m-methylphenyl)-1,1,1-tris(phenylthio)butane (111171-83-6) → 6-methyl-3,4-dihydronaphthalen-1(2H)-one (51015-29-3)

Guidance literature:

With silver trifluoromethanesulfonate; In dichloromethane; for 20h; Ambient temperature;

DOI:10.1016/S0040-4020(01)81496-4

upstream raw materials:

4-(m-tolyl)butanoic acid

1-Oxo-6-methyl-1,2,3,4,7,8-hexahydro-naphthalin

tetramethylstannane

5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate

Downstream raw materials:

6-methyl-1-phenylnaphthalene

6-methyl-1,2,3,4-tetrahydronaphthalen-1-amine

7-methyl-4-phenyl-1,2-dihydronaphthalene

Refernces

• 1、 Shim, Seung-Bo,Ko, Yoon-Joo,Yoo, Byeong-Wook,Lim, Chang-Keun,Shin, Jung-Hyu. "Intramolecular ionic Diels-Alder reactions of α-acetylenic acetals". . p. 8154 - 8156. Retrieved 2004.
• 2、 -. "MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF". . . Retrieved 2021/01/23.
• 3、 Morita, Shunya,Yoshimura, Tomoyuki,Matsuo, Jun-ichi. "Intramolecular Büchner reaction and oxidative aromatization with SeO2 or O2". . p. 729 - 732. Retrieved 2019/07/31.