Technology Process of Benzamide, 2-bromo-4,6-dimethoxy-
There total 4 articles about Benzamide, 2-bromo-4,6-dimethoxy- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-bromo-4,6-dimethoxybenzoic acid;
With
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran;
at 20 ℃;
for 4h;
With
ammonia;
In
tetrahydrofuran;
for 1h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene / tert-butyl alcohol / 1 h / 20 °C
2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / tetrahydrofuran / 4 h / 20 °C
2.2: 1 h
With
4-methyl-morpholine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trichlorophosphate / 4 h / 100 °C / Inert atmosphere; Cooling with ice
2.1: sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene / tert-butyl alcohol / 1 h / 20 °C
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / tetrahydrofuran / 4 h / 20 °C
3.2: 1 h
With
4-methyl-morpholine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trichlorophosphate;
In
tetrahydrofuran; tert-butyl alcohol;