3,3-Diethoxypropanal

Base Information

• Chemical Name: 3,3-Diethoxypropanal
• CAS No.: 6367-37-9
• Molecular Formula: C7H14O3
• Molecular Weight: 146.186
• DSSTox Substance ID: DTXSID90501596
• Nikkaji Number: J1.311.808F
• Wikidata: Q82354064
• Mol file: 6367-37-9.mol

Synonyms:3,3-diethoxypropanal;6367-37-9;Propanal, 3,3-diethoxy-;3,3-diethoxypropionaldehyde;3,3-diethoxy-propionaldehyde;SCHEMBL440377;DTXSID90501596;MFCD24445070;SY269124;FT-0700961;E86593

Chemical Property of 3,3-Diethoxypropanal

Chemical Property:

• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 146.094294304
• Heavy Atom Count: 10
• Complexity: 76.9

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(CC=O)OCC

Technology Process of 3,3-Diethoxypropanal

There total 1 articles about 3,3-Diethoxypropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3,3-diethoxypropan-1-ol (16777-87-0) → 3,3-diethoxypropanal (6367-37-9) + 3-ethoxyacrolein (19060-08-3)

Guidance literature:

With dipyridinium dichromate; 3 A molecular sieve; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(01)88513-6

Reference yield: 72.0%

3,3-diethoxypropanal (6367-37-9) + phenylacetylene (536-74-3) → 5,5-diethoxy-1-phenylpent-1-yn-3-ol

Guidance literature:

phenylacetylene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

3,3-diethoxypropanal; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 0.583333h; Inert atmosphere;

DOI:10.1021/acs.joc.9b00988

Reference yield: 65.0%

3,3-diethoxypropanal (6367-37-9) + (R)-(+)-(1-tert-butyldimethylsilyloxy-1-phenyl)butan-2-one (288374-67-4) → (3R,4S,6R)-1,1-diethoxy-3-hydroxy-4-methyl-5-oxo-6-[(tert-butyl-dimethylsilyl)oxy]-6-phenylhexane (288374-68-5)

Guidance literature:

(R)-(+)-(1-tert-butyldimethylsilyloxy-1-phenyl)butan-2-one; With di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -78 - 0 ℃;

3,3-diethoxypropanal; In dichloromethane; at -78 - 0 ℃;

DOI:10.1016/S0040-4020(00)00255-6

upstream raw materials:

3,3-diethoxypropan-1-ol

Downstream raw materials:

malondialdehyde bis(diethyl acetal)

3-ethoxyacrolein

Ethyl p-(3,3-Diethoxypropylamino)benzoate

((Z)-(1R,2S)-1-Benzyloxymethyl-2-methyl-pent-3-enyloxy)-tert-butyl-dimethyl-silane

Refernces