2,4-Dimethylol phenol

Base Information

• Chemical Name: 2,4-Dimethylol phenol
• CAS No.: 2937-60-2
• Molecular Formula: C8H10 O3
• Molecular Weight: 154.166
• Hs Code.: 2906299090
• European Community (EC) Number: 220-920-8
• UNII: K2V6A19T77
• DSSTox Substance ID: DTXSID40183604
• Nikkaji Number: J28.480G
• Wikidata: Q27281868
• Mol file: 2937-60-2.mol

Synonyms:2,4-di-(hydroxymethyl)phenol;2,4-dimethylol phenol

Chemical Property of 2,4-Dimethylol phenol

Chemical Property:

• Boiling Point: 333.1°Cat760mmHg
• Flash Point: 169.3°C
• PSA: 60.69000
• Density: 1.334g/cm³
• LogP: 0.37680
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 154.062994177
• Heavy Atom Count: 11
• Complexity: 116

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dimethylolphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1CO)CO)O
• Description: 2,4-Dimethylol phenol in a compound of resins based on phenol and formaldehyde. Cross reactivity is possible with other phenol derivative molecules.

Technology Process of 2,4-Dimethylol phenol

There total 5 articles about 2,4-Dimethylol phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 4-hydroxyisophthalate (5985-24-0) → 2,4-bis(hydroxymethyl)phenol (2937-60-2)

Guidance literature:

With lithium aluminium tetrahydride;

Reference yield:

4-acetoxy-isophthalic acid dimethyl ester (71932-29-1) → 2,4-bis(hydroxymethyl)phenol (2937-60-2)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01144a030

Reference yield:

2-chloro-4,6-bis-hydroxymethyl-phenol (22002-29-5) → 2,4-bis(hydroxymethyl)phenol (2937-60-2)

Guidance literature:

With methanol; sodium hydroxide; nickel; Hydrogenation;

upstream raw materials:

dimethyl 4-hydroxyisophthalate

2-chloro-4,6-bis-hydroxymethyl-phenol

4-acetoxy-isophthalic acid dimethyl ester

phenol

Downstream raw materials:

2,4,6-tris(hydroxymethyl)phenol

2,4-Bis-(2-hydroxy-3,5-dimethyl-benzyl)-phenol

2-azidomethyl-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-phenol

pentanedioic acid mono-{2-azidomethyl-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-phenyl} ester

Refernces