2-Hydroxybenzene-1,3,5-trimethanol

Base Information

• Chemical Name: 2-Hydroxybenzene-1,3,5-trimethanol
• CAS No.: 2937-61-3
• Molecular Formula: C9H12O4
• Molecular Weight: 184.192
• Hs Code.: 2907199090
• European Community (EC) Number: 220-921-3
• UNII: 4JW5B05026
• DSSTox Substance ID: DTXSID00183605
• Nikkaji Number: J28.476I
• Wikidata: Q27259789
• Mol file: 2937-61-3.mol

Synonyms:2,4,6-trimethylol phenol

Chemical Property of 2-Hydroxybenzene-1,3,5-trimethanol

Chemical Property:

• Vapor Pressure: 1.09E-07mmHg at 25°C
• Melting Point: 70-75 °C(Solv: benzene (71-43-2))
• Refractive Index: 1.655
• Boiling Point: 416.7 °C at 760 mmHg
• PKA: 9.69±0.23(Predicted)
• Flash Point: 213 °C
• PSA: 80.92000
• Density: 1.424 g/cm³
• LogP: -0.13090
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 184.07355886
• Heavy Atom Count: 13
• Complexity: 137

Purity/Quality:

98%Min ^*data from raw suppliers

1,3,5-BENZENETRIMETHANOL,2-HYDROXY- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1CO)O)CO)CO
• Description: Trimethylol phenol is an allergen in resins based on phenol and formaldehyde. Cross reactivity is possible with other phenol derivative molecules.

Technology Process of 2-Hydroxybenzene-1,3,5-trimethanol

There total 12 articles about 2-Hydroxybenzene-1,3,5-trimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenol (108-95-2,27073-41-2) → 2,4,6-tris(hydroxymethyl)phenol (2937-61-3)

Guidance literature:

With lithium hydroxide;

Reference yield:

2-acetoxy-benzene-1,3,5-tricarboxylic acid triethyl ester → 2,4,6-tris(hydroxymethyl)phenol (2937-61-3)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01144a030

Reference yield:

2,4,6-triacetoxymethylphenyl acetate (2219-90-1) → 2,4,6-tris(hydroxymethyl)phenol (2937-61-3)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1039/jr9540002731

upstream raw materials:

formaldehyd

(4-hydroxyphenyl)methanol

2,4-bis(hydroxymethyl)phenol

2,4,6-triacetoxymethylphenyl acetate

Downstream raw materials:

2-methoxy-benzene-1,3,5-tricarboxylic acid trimethyl ester

2,4,6-Trisalicyl-phenol

C₂₁H₃₉N₃O₇

Refernces

• 1、 Zhao, Xiaochen,Zhang, Qiang,Zhang, Bingsen,Chen, Cheng-Meng,Xu, Jinming,Wang, Aiqin,Su, Dang Sheng,Zhang, Tao. "Decorated resol derived mesoporous carbon: Highly ordered microstructure, rich boron incorporation, and excellent electrochemical capacitance". . p. 3578 - 3584. Retrieved 2013.
• 2、 -. "A cross-linking agent and cross-linked can be charged with high temperature resistant gel preparation method". Paragraph 0051; 0053. . Retrieved 2017/04/11.