Technology Process of 4-(Benzylamino)-1-methyl-1H-imidazole-5-carboxamide
There total 2 articles about 4-(Benzylamino)-1-methyl-1H-imidazole-5-carboxamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
for 2h;
Heating;
- Guidance literature:
-
1.Prep. Sulfonat VI, NaOH;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: aq. AcOH-AcONa buffer, 10 percent aq. NaOH / ethyl acetate / 3.5 h / Ambient temperature; pH 5.2-5.3
2: 0.5 N aq. NaOH / 0.17 h / Heating
3: 1.) K2CO3 / 1.) DMF, 80 deg C, 1 h, 2.) room temperature, 3 h
4: 70 percent / H2, 70percent aq. HClO4 / 10percent Pd/C / acetic acid / 760 Torr / 1.) 40 deg C, 4 h, 2.) 60 deg C, 13 h
With
sodium hydroxide; perchloric acid; AcOH-AcONa buffer; hydrogen; potassium carbonate;
palladium on activated charcoal;
In
acetic acid; ethyl acetate;
DOI:10.1248/cpb.39.2855
