6-BENZYLAMINO-7-METHYLPURINE

Base Information

• Chemical Name: 6-BENZYLAMINO-7-METHYLPURINE
• CAS No.: 77868-58-7
• Molecular Formula: C13H13 N5
• Molecular Weight: 239.28
• Hs Code.: 2933990090
• Mol file: 77868-58-7.mol

Synonyms:6-Benzylamino-7-methylpurine

Chemical Property of 6-BENZYLAMINO-7-METHYLPURINE

Chemical Property:

• PSA: 55.63000
• LogP: 2.04840

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-BENZYLAMINO-7-METHYLPURINE

There total 6 articles about 6-BENZYLAMINO-7-METHYLPURINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

4-benzamido-6-benzylamino-5-(N-methylformamido)pyrimidine (77868-56-5) → 6-benzylamino-7-methylpurine (77868-58-7) + N6-benzyl-7-methyl-8-phenyladenine

Guidance literature:

With sodium hydroxide; for 2h; Heating;

Reference yield: 3.0%

3-benzyl-7-methyladenine hydriodide → 6-benzylamino-7-methylpurine (77868-58-7) + 4-(N-benzylamino)-1-methyl-1H-imidazole-5-carboxamide (64995-66-0)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

Reference yield:

N6-benzoyl-9-benzyl-7-methyladeninium iodide (77868-52-1) → 6-benzylamino-7-methylpurine (77868-58-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / 0.25M NaOH / ethanol / 0.5 h / Ambient temperature

2: 7 percent / 10percent HCl / 2 h / 100 °C

With hydrogenchloride; sodium hydroxide; In ethanol;

upstream raw materials:

4-benzamido-6-benzylamino-5-(N-methylformamido)pyrimidine

6-chloropurine

benzylamine

methyl iodide

Refernces

• 1、 Fujii, Tozo,Saito, Tohru,Inoue, Isao,Kumazawa, Yukinari,Tamura, Katsumi. "Purines. XXX. Ring Fission of 3,7-Dialkyladenines by Alkaline Hydrolysis". . p. 107 - 117. Retrieved 2007/10/02.
• 2、 Maki, Yoshifumi,Suzuki, Mikio,Kameyama, Keiji,Kawai, Masaru,Suzuki, Munehiro,Sako, Magoichi. "N7-ALKYLATION AND RING-TRNSFORMATION OF N6-ACYL-9-SUBSTITUTED ADENINES". . p. 895 - 898. Retrieved 2007/10/02.