5-Methoxyuracil

Base Information Edit

Chemical Name:5-Methoxyuracil
CAS No.:6623-81-0
Molecular Formula:C5H6N2O3
Molecular Weight:142.114
Hs Code.:2933599090
European Community (EC) Number:229-580-5
NSC Number:55452
UNII:79DD14XTQR
DSSTox Substance ID:DTXSID20216424
Nikkaji Number:J39.036D
Wikidata:Q27266752
Mol file:6623-81-0.mol

Synonyms:6623-81-0;5-Methoxyuracil;2,4-Dihydroxy-5-methoxypyrimidine;5-Methoxy-2,4-pyrimidinediol;5-methoxypyrimidine-2,4-diol;5-methoxypyrimidine-2,4(1H,3H)-dione;5-methoxy-1H-pyrimidine-2,4-dione;5-Methoxy-2,4-dihydroxypyrimidine;5-Methoxy-2,4-pyrimidinedione;1882546-41-9;2,4(1H,3H)-pyrimidinedione, 5-methoxy-;5-METHOXYPYRIMIDINE-2,4-DIONE;MFCD03428618;UNII-79DD14XTQR;79DD14XTQR;EINECS 229-580-5;NSC-55452;5-methoxy-1,2,3,4-tetrahydropyrimidine-2,4-dione;5-Methoxypyrimidine-2,4(1H,3H)-dione (5-Methoxyuracil);NSC55452;NSC 55452;5-METHOXY-2,4-DIHYDROXY PYRIMIDINE;URACIL, 5-METHOXY-;SCHEMBL102177;5-Methoxy-pyrimidine-2,4-diol;DTXSID20216424;BCP13246;CS-D0616;2,4-Dihydroxy-5-Methoxy Pyrimidine;BBL100647;MFCD00187903;STL554441;AKOS005073641;AKOS005254714;GS-6607;SB57433;SS-2971;5-methoxy-2,4(1H,3H)-pyrimidinedione;AC-25256;SY021296;5-(Methoxy)-2,4(1H,3H)-pyrimidinedione;A8944;AM20100604;D4599;FLUOROURACIL IMPURITY D [EP IMPURITY];FT-0601165;EN300-85913;L10025;AO-324/25087001;W-202959;W-203452;Q27266752;Z1198162869

Suppliers and Price of 5-Methoxyuracil

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Methoxyuracil
2.5g
$ 446.00

TRC
5-Methoxyuracil
2g
$ 135.00

TCI Chemical
2,4-Dihydroxy-5-methoxypyrimidine >98.0%(GC)(T)
5g
$ 264.00

TCI Chemical
2,4-Dihydroxy-5-methoxypyrimidine >98.0%(GC)(T)
1g
$ 87.00

Medical Isotopes, Inc.
5-Methoxyuracil
25 g
$ 1075.00

Matrix Scientific
5-Methoxy-2,4-pyrimidinediol >95%
1g
$ 10.00

Matrix Scientific
5-Methoxy-2,4-pyrimidinediol >95%
5g
$ 19.00

Matrix Scientific
5-Methoxy-2,4-pyrimidinediol >95%
25g
$ 49.00

Crysdot
2,4-Dihydroxy-5-methoxypyrimidine 96%
100g
$ 164.00

ChemScene
2,4-Dihydroxy-5-methoxypyrimidine
25g
$ 50.00

Total 109 raw suppliers

Chemical Property of 5-Methoxyuracil Edit

Chemical Property:

Appearance/Colour:Beige powder
Vapor Pressure:1.85E-10mmHg at 25°C
Melting Point:344°C(lit.)
Refractive Index:1.628
Boiling Point:508.5oC at 760 mmHg
PKA:8.17±0.10(Predicted)
Flash Point:207.7oC
PSA：74.95000
Density:1.39 g/cm³
LogP:-0.92820
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:DMSO (Slightly, Heated), Water (Slightly, Heated)
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:142.03784206
Heavy Atom Count:10
Complexity:209

Purity/Quality:: 5-Methoxyuracil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=CNC(=O)NC1=O
Uses 5-Methoxy-2,4-pyrimidinediol is used as building block in chemical synthesis, it is also used in the preparation of nucleosides. 5-Methoxyuracil is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides. 5-Methoxyuracil (Fluorouracil EP Impurity D) is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides.

Technology Process of 5-Methoxyuracil

There total 11 articles about 5-Methoxyuracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 6939-11-3
5-methoxy-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

: 6623-81-0
5-methoxyuracil

Guidance literature:: 5-methoxy-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; With water; chloroacetic acid; for 2h; Heating / reflux;

With hydrogenchloride; water; for 16h; Heating / reflux;