TERT-BUTYL CINNAMATE 98

Base Information

• Chemical Name: TERT-BUTYL CINNAMATE 98
• CAS No.: 7042-36-6
• Molecular Formula: C₁₃H₁₆O₂
• Molecular Weight: 204.269
• Mol file: 7042-36-6.mol

Synonyms:

Chemical Property of TERT-BUTYL CINNAMATE 98

Chemical Property:

• Boiling Point: 85 °C/0.12 mmHg (lit.)
• Flash Point: 230?°F
• PSA: 26.30000
• Density: 1 g/mL at 25 °C (lit.)
• LogP: 3.04150

Purity/Quality:

95% ^*data from raw suppliers

tert-Butyl cinnamate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of TERT-BUTYL CINNAMATE 98

There total 21 articles about TERT-BUTYL CINNAMATE 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mono-tert-butyl malonate (40052-13-9) + benzaldehyde (100-52-7) → (Z)-tert-butyl 3-phenylprop-2-enoate (7042-36-6,14990-09-1,68872-73-1) + tert-butyl cinnamate (14990-09-1)

Guidance literature:

With piperidine; dmap; In N,N-dimethyl-formamide; at 25 ℃; Title compound not separated from byproducts;

DOI:10.1002/adsc.200505196

Reference yield:

iodobenzene (591-50-4) + tert-Butyl acrylate (1663-39-4,25232-27-3) → (Z)-tert-butyl 3-phenylprop-2-enoate (7042-36-6,14990-09-1,68872-73-1) + tert-butyl cinnamate (14990-09-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 72h; Overall yield = 90 %; stereoselective reaction; Irradiation;

DOI:10.1039/c3cy00602f

Reference yield:

tert-Butyl chloroacetate (107-59-5) + benzaldehyde (100-52-7) → (Z)-tert-butyl 3-phenylprop-2-enoate (7042-36-6,14990-09-1,68872-73-1) + tert-butyl cinnamate (14990-09-1)

Guidance literature:

With triphenylphosphine; nanocrystalline aerogel prepared MgO; In N,N-dimethyl-formamide; at 20 ℃; for 32h; Title compound not separated from byproducts;

DOI:10.1002/adsc.200606001

upstream raw materials:

tert-butyl cinnamate

(E)-3-Phenyl-2-trimethylsilanyl-acrylic acid tert-butyl ester

erythro-tert-butyl 3-hydroxy-3-phenyl-2-(trimethylgermyl)propanoate

tert-butyl (trimethylgermyl)acetate

Downstream raw materials:

rac-di-tert-butyl (2R,3S)-2-methyl-3-phenylpentanedioate

di-tert-butyl rac-(2R,3R)-2-methyl-3-phenylpentanedioate

(2R,3S)-N-benzoyl-3-phenylisoserine

t-butyl cis-β-phenylglycidate

Refernces

• 1、 Tyagi, Vikas,Fasan, Rudi. "Myoglobin-catalyzed olefination of aldehydes". supporting information. p. 2512 - 2516. Retrieved 2016/02/18.
• 2、 Soni, Saurabh S.,Kotadia, Deepali A.. "Time-dependent stereoselective Heck reaction using mesoporous Pd/TiO 2 nanoparticles catalyst under sunlight". . p. 510 - 515. Retrieved 2014/02/14.