Monomethyl phosphate

Base Information

• Chemical Name: Monomethyl phosphate
• CAS No.: 7361-70-8
• Molecular Formula: CH3O4P
• Molecular Weight: 110.006
• DSSTox Substance ID: DTXSID001265106
• Nikkaji Number: J2.975.720H,J901.432B
• Wikidata: Q27126888
• Mol file: 7361-70-8.mol

Synonyms:methyl phosphate disodium salt, hexahydrate;methylphosphate;methylphosphate diammonium salt;methylphosphate diammonium salt, dihydrate;methylphosphate dipotassium salt;methylphosphate monoammonium salt;methylphosphate monopotassium salt;methylphosphate monosodium salt;methylphosphate vanadium salt;methylphosphate, phosporic-(17)O-(18)O acid (16)O-methyl ester, disodium salt, (R)-isomer;monomethyl phosphate

Chemical Property of Monomethyl phosphate

Chemical Property:

• XLogP3: -1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 109.97689557
• Heavy Atom Count: 6
• Complexity: 60.1

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COP(=O)([O-])[O-]

Technology Process of Monomethyl phosphate

There total 2 articles about Monomethyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-chloro-4-nitrophenyl phosphate (58286-59-2) → 2-chloro-4-nitrophenol (619-08-9) + methyl 2-chloro-4-nitrophenyl phosphate (7361-70-8)

Guidance literature:

With water; In ethanol; at 25 ℃; Concentration; Reagent/catalyst; Kinetics;

DOI:10.1021/ja805801j

Reference yield:

(3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate (174867-64-2) → methyl 2-chloro-4-nitrophenyl phosphate (7361-70-8) + methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenol cyclic phosphate (174867-53-9) + C11H16O5P(1-) + tert-butylammonium 3,4-dichlorophenoxymethyl methyl phosphate

Guidance literature:

With potassium hydroxide; In water; acetonitrile; at 39 ℃; for 0.5h; Rate constant; Mechanism; Product distribution; various reaction conditions;

upstream raw materials:

(3,4-dichlorophenoxy)methyl 2-(1-hydroxy-1-methylethyl)-4-methylphenyl methyl phosphate

methyl 2-chloro-4-nitrophenyl phosphate

Refernces

• 1、 Kirby, Anthony J.,Marriott, Robert E.. "Rapid intramolecular and C-O cleavage reactions of a phosphate triester catalysed by a neighbouring hydroxyl group". . p. 56 - 62. Retrieved 2007/10/03.